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Jdp2
Gene Detail
 Symbol
Name
ID
Jdp2
Jun dimerization protein 2
MGI:1932093
Synonyms Jundm2, TIF
Feature Type protein coding gene
Genetic Map
Chromosome 12
39.74 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr12:85599105-85639878 bp, + strand
From NCBI annotation of GRCm38

  40774 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12787  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Jdp2

Human
homologs
Human Homolog JDP2, Jun dimerization protein 2
NCBI Gene ID 122953
neXtProt AC  NX_Q8WYK2
Human Synonyms  JUNDM2
Human Chr (Location)  14q24.3; chr14:75427806-75472701 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(7) Targeted(6)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit increased white adipose tissue differentiation, short tail, and enhanced would healing due to increased cell proliferation.
 
Interactions
Jdp2 interacts with 165 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process negative regulation of fat cell differentiation, negative regulation of transcription from RNA polymerase II promoter, ...
Component nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (283)    Tissues (89)    Images (29)
Theiler Stages: 10, 17, 18, 21, 23, 25, 28
Assay TypeResults
RNA in situ 268
Northern blot 15
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000034271 (Evidence)
Entrez Gene81703 (Evidence)
DFCITC1585978, TC1593883
DoTSDT.101348060, DT.60106756, DT.87068255
NIA Mouse Gene IndexU014212
Consensus CDS ProjectCCDS26060.1
International Mouse Knockout Project StatusJdp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 81703 NCBI Gene Model | MGI Sequence Detail 40774 C57BL/6J ±  kb
transcript NM_030887 RefSeq | MGI Sequence Detail 1662 Not Specified 
polypeptide P97875 UniProt | EBI | MGI Sequence Detail 163 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR000837 Fos transforming protein
Protein Ontology PR:000009210 jun dimerization protein 2
Graphical View of Protein Domain Structure
References (Earliest) J:67261 Jin C, et al., Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2. FEBS Lett. 2001 Jan 26;489(1):34-41
(Latest) J:210368 Yao C, et al., The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis. J Biol Chem. 2014 Mar 7;289(10):6775-90
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory