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Jdp2
Gene Detail
Symbol

Name
ID
Jdp2
Jun dimerization protein 2
MGI:1932093
Synonyms
Jundm2, TIF
Feature Type
protein coding gene
Genetic Map
Chromosome 12
39.74 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr12:85599105-85639878 bp, + strand
From Ensembl annotation of GRCm38

  40774 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12787  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: JDP2
Gene Tree: Jdp2

Human
homologs
JDP2, Jun dimerization protein 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 122953
neXtProt AC: NX_Q8WYK2

Human Synonyms: JUNDM2

Human Chr (Location): 14q24.3; chr14:75427806-75472701 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(7) Targeted(6)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit increased white adipose tissue differentiation, short tail, and enhanced would healing due to increased cell proliferation.
 
Interactions
Jdp2 interacts with 165 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (283)    Tissues (89)    Images (29)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 268
Northern blot 15
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA JDP2 ZFIN jdp2b    NEW 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000034271 (Evidence)
Entrez Gene 81703 (Evidence)
DFCI TC1585978, TC1593883
DoTS DT.101348060, DT.60106756, DT.87068255
NIA Mouse Gene Index U014212
Consensus CDS Project CCDS26060.1
International Mouse Phenotyping Consortium Status Jdp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034271 Ensembl Gene Model | MGI Sequence Detail 40774 C57BL/6J ±  kb
transcript ENSMUST00000177587 Ensembl | MGI Sequence Detail 1567 Not Applicable 
polypeptide ENSMUSP00000136823 Ensembl | MGI Sequence Detail 163 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(14) UniProt(3)
Polymorphisms
SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000837 AP-1 transcription factor
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR029819 Jun dimerization protein 2
Protein Ontology PR:000009210 jun dimerization protein 2
References
(Earliest) J:67261 Jin C, et al., Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2. FEBS Lett. 2001 Jan 26;489(1):34-41
(Latest) J:210368 Yao C, et al., The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis. J Biol Chem. 2014 Mar 7;289(10):6775-90
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory