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Ghdc Gene Detail
Summary
  • Symbol
    Ghdc
  • Name
    GH3 domain containing
  • Synonyms
    D11Lgp1e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931556
    NCBI Gene: 80860
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100766032-100770957 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 63.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931556
protein coding gene Chr11:100766026-100770982 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019170
protein coding gene Chr11:103539346-103544271 (-)
A/J MGP_AJ_G0019138
protein coding gene Chr11:99218512-99223508 (-)
AKR/J MGP_AKRJ_G0019107
protein coding gene Chr11:102299745-102308873 (-)
BALB/cJ MGP_BALBcJ_G0019112
protein coding gene Chr11:99704726-99709699 (-)
C3H/HeJ MGP_C3HHeJ_G0018921
protein coding gene Chr11:102463188-102468176 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019561
protein coding gene Chr11:106747402-106752327 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017187
protein coding gene Chr11:96636469-96641103 (-)
CAST/EiJ MGP_CASTEiJ_G0018475
protein coding gene Chr11:103448787-103453683 (-)
CBA/J MGP_CBAJ_G0018890
protein coding gene Chr11:111204832-111212939 (-)
DBA/2J MGP_DBA2J_G0019002
protein coding gene Chr11:98754480-98759342 (-)
FVB/NJ MGP_FVBNJ_G0018992
protein coding gene Chr11:98293786-98298731 (-)
LP/J MGP_LPJ_G0019071
protein coding gene Chr11:104098020-104103599 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019023
protein coding gene Chr11:110787634-110792563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019599
protein coding gene Chr11:102615000-102619925 (-)
PWK/PhJ MGP_PWKPhJ_G0018238
protein coding gene Chr11:99793808-99799048 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018030
protein coding gene Chr11:102356957-102361829 (-)
WSB/EiJ MGP_WSBEiJ_G0018524
protein coding gene Chr11:102605148-102610005 (-)



Homology
more
  • Human Ortholog
    GHDC, GH3 domain containing
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GHDC, GH3 domain containing
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D11LGP1, LGP1
  • Links
    NCBI Gene ID: 84514
    neXtProt AC: NX_Q8N2G8
    UniProt: Q8N2G8

  • Chr Location
    17q21.2; chr17:42189087-42194532 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017747 Ensembl Gene Model | MGI Sequence Detail 4926 C57BL/6J ±  kb
transcript ENSMUST00000017891 Ensembl | MGI Sequence Detail 2462 Not Applicable  
polypeptide ENSMUSP00000017891 Ensembl | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:50799 Liu P, et al., Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 1998 Nov;150(3):1155-68
  • Latest
    J:232020 Ermakova O, et al., Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med. 2011 Jan;3(1):50-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory