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Hist1h1a Gene Detail
Summary
  • Symbol
    Hist1h1a
  • Name
    histone cluster 1, H1a
  • Synonyms
    H1.1, H1a, H1f1, H1var3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931523
    NCBI Gene: 80838
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: HIST1H1A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23763666-23764406 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A3.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931523
protein coding gene Chr13:23763666-23764412 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020367
protein coding gene Chr13:21208768-21209409 (+)
A/J MGP_AJ_G0020316
protein coding gene Chr13:20817667-20818308 (+)
AKR/J MGP_AKRJ_G0020296
protein coding gene Chr13:21070519-21071160 (+)
BALB/cJ MGP_BALBcJ_G0020314
protein coding gene Chr13:20813342-20813983 (+)
C3H/HeJ MGP_C3HHeJ_G0020118
protein coding gene Chr13:21143096-21143737 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020751
protein coding gene Chr13:21988531-21989172 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018339
protein coding gene Chr13:19590654-19591295 (+)
CAST/EiJ MGP_CASTEiJ_G0026775
protein coding gene Chr3:95905329-95905970 (+)
CBA/J MGP_CBAJ_G0020072
protein coding gene Chr13:22846351-22846992 (+)
DBA/2J MGP_DBA2J_G0020198
protein coding gene Chr13:20345332-20345973 (+)
FVB/NJ MGP_FVBNJ_G0020182
protein coding gene Chr13:19996874-19997515 (+)
LP/J MGP_LPJ_G0020271
protein coding gene Chr13:21517775-21518416 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020209
protein coding gene Chr13:23137716-23138357 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020793
protein coding gene Chr13:20923198-20923839 (+)
PWK/PhJ MGP_PWKPhJ_G0019389
protein coding gene Chr13:20376797-20377438 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019206
protein coding gene Chr13:19728787-19729428 (+)
WSB/EiJ MGP_WSBEiJ_G0019695
protein coding gene Chr13:21061256-21061897 (+)



Homology
more
  • Human Ortholog
    HIST1H1A, histone cluster 1 H1 family member a
  • Vertebrate Orthologs
    3
  • Human Ortholog
    HIST1H1A, histone cluster 1 H1 family member a
    Orthology source: HGNC
  • Synonyms
    H1.1, H1A, H1F1, HIST1
  • Links
    NCBI Gene ID: 3024
    neXtProt AC: NX_Q02539
    UniProt: Q02539

  • Chr Location
    6p22.2; chr6:26017032-26017812 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    14 phenotype references
Mice homozygous for a targeted null mutation are viable, fertile and do not exhibit any defects in the reproductive system or in spermatogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049539 Ensembl Gene Model | MGI Sequence Detail 741 C57BL/6J ±  kb
transcript ENSMUST00000055770 Ensembl | MGI Sequence Detail 741 Not Applicable  
polypeptide ENSMUSP00000062030 Ensembl | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:256001 Jung EM, et al., Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory