About   Help   FAQ
Clca3a2
Gene Detail
Symbol

Name
ID
Clca3a2
chloride channel calcium activated 3A2
MGI:1931471
Synonyms
Clca2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
69.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:144796559-144819494 bp, - strand
From VEGA annotation of GRCm38

  22936 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77224  Vertebrate Homology Class
2 mouse; 1 rat; 1 rhesus macaque; 2 cattle; 1 dog; 1 chicken; 5 western clawed frog; 1 zebrafish

Protein SuperFamily: calcium-activated chloride channel
Gene Tree: Clca3a2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Clca3a2 interacts with 194 markers (Mir1b, Mir10a, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process anoikis, chloride transmembrane transport, ...
Component integral component of plasma membrane
Function intracellular calcium activated chloride channel activity
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (186)    Tissues (55)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 137
RT-PCR 49
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(7) Primer pair(6) Other(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026565 (Evidence)
Ensembl Gene ModelENSMUSG00000028262 (Evidence)
Entrez Gene80797 (Evidence)
Consensus CDS ProjectCCDS17887.1
International Mouse Knockout Project StatusClca3a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026565 VEGA Gene Model | MGI Sequence Detail 22936 C57BL/6J ±  kb
transcript OTTMUST00000065727 VEGA | MGI Sequence Detail 3654 Not Applicable 
polypeptide OTTMUSP00000032794 VEGA | MGI Sequence Detail 902 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(8)
Polymorphisms
SNPs within 2kb(150 from dbSNP Build 137)    SNPs within 2kb including multiple locations(184)
Protein-related
information
ResourceIDDescription
InterPro IPR004727 Calcium-activated chloride channel protein
InterPro IPR013642 Chloride channel calcium-activated
InterPro IPR015394 Domain of unknown function DUF1973
InterPro IPR003961 Fibronectin, type III
InterPro IPR002035 von Willebrand factor, type A
References
(Earliest) J:58395 Lee D, et al., Induction of mouse Ca(2+)-sensitive chloride channel 2 gene during involution of mammary gland. Biochem Biophys Res Commun. 1999 Nov 2;264(3):933-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory