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Selk
Gene Detail
Symbol

Name
ID
Selk (Interim)
selenoprotein K
MGI:1931466
Synonyms
1110001C03Rik, 30kDa, HSPC030
Feature Type
protein coding gene
Genetic Map
Chromosome 14
18.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:29968308-29975074 bp, + strand
From VEGA annotation of GRCm38

  6767 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56870  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: SELK
Gene Tree: Selk

Human
homologs
SELK, selenoprotein K
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 58515
neXtProt AC: NX_Q9Y6D0

Human Synonyms: HSPC030, HSPC297, SelK

Human Chr (Location): 3p21.31; chr3:53885199-53891962 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Targeted(6)
 
Mice homozygous for a knock-out allele exhibit impaired T cell, neutrophil, and macrophage calcium flux and increased susceptibility to viral infection.
 
Interactions
Selk interacts with 152 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
cDNA source data(108)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase selk    NEW 
Molecular
reagents
All nucleic(108) cDNA(108)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000020974 (Evidence)
Ensembl Gene Model ENSMUSG00000042682 (Evidence)
Entrez Gene 80795 (Evidence)
UniGene 104491
DFCI TC1696016, TC1574392
DoTS DT.94364647, DT.534759
NIA Mouse Gene Index U219820, U074359, U015432
Consensus CDS Project CCDS36844.1
International Mouse Phenotyping Consortium Status Selk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020974 VEGA Gene Model | MGI Sequence Detail 6767 C57BL/6J ±  kb
transcript OTTMUST00000049602 VEGA | MGI Sequence Detail 1090 Not Applicable 
polypeptide OTTMUSP00000023011 VEGA | MGI Sequence Detail 94 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024491 Selenoprotein SelK/SelG
Protein Ontology PR:000014609 selenoprotein K
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:216755 Fredericks GJ, et al., Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16478-83
All references(40)
Other
accession IDs
MGI:1913387, MGI:2145576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory