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Selk
Gene Detail
 Symbol
Name
ID
Selk (Interim)
selenoprotein K
MGI:1931466
Synonyms 1110001C03Rik, 30kDa, HSPC030
Feature Type protein coding gene
Genetic Map
Chromosome 14
18.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:29968308-29975074 bp, + strand
From VEGA annotation of GRCm38

  6767 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56870  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Selk

Human
homologs
Human Homolog SELK, selenoprotein K
NCBI Gene ID 58515
neXtProt AC  NX_Q9Y6D0
Human Synonyms  HSPC297, SelK
Human Chr (Location)  3p21.31; chr3:53885199-53891962 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Targeted(6)
 
Mice homozygous for a knock-out allele exhibit impaired T cell, neutrophil, and macrophage calcium flux and increased susceptibility to viral infection.
 
Interactions
Selk interacts with 152 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process calcium ion transport, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(108)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(108) cDNA(108)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020974 (Evidence)
Ensembl Gene ModelENSMUSG00000042682 (Evidence)
Entrez Gene80795 (Evidence)
UniGene104491
DFCITC1574392, TC1696016
DoTSDT.534759, DT.94364647
NIA Mouse Gene IndexU015432, U074359, U219820
Consensus CDS ProjectCCDS36844.1
International Mouse Knockout Project StatusSelk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020974 VEGA Gene Model | MGI Sequence Detail 6767 C57BL/6J ±  kb
transcript OTTMUST00000049602 VEGA | MGI Sequence Detail 1090 Not Applicable 
polypeptide OTTMUSP00000023011 VEGA | MGI Sequence Detail 94 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024491 Selenoprotein SelK/SelG
Protein Ontology PR:000014609 selenoprotein K
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:200795 Meiler S, et al., Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis. J Leukoc Biol. 2013 May;93(5):771-80
All references(41)
Other
accession IDs
MGI:1913387, MGI:2145576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory