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Nkg7 Gene Detail
Summary
  • Symbol
    Nkg7
  • Name
    natural killer cell group 7 sequence
  • Synonyms
    2500004F03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931250
    NCBI Gene: 72310
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:43437138-43438246 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.25 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931250
protein coding gene Chr7:43437073-43438249 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032123
protein coding gene Chr7:43451014-43452190 (+)
A/J MGP_AJ_G0032108
protein coding gene Chr7:42564004-42565180 (+)
AKR/J MGP_AKRJ_G0032038
protein coding gene Chr7:43933771-43934947 (+)
BALB/cJ MGP_BALBcJ_G0032113
protein coding gene Chr7:42678774-42679950 (+)
C3H/HeJ MGP_C3HHeJ_G0031829
protein coding gene Chr7:44433317-44434493 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032597
protein coding gene Chr7:45644739-45645915 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029620
protein coding gene Chr7:44685654-44686818 (+)
CAST/EiJ MGP_CASTEiJ_G0031159
protein coding gene Chr7:35608283-35609459 (+)
CBA/J MGP_CBAJ_G0031798
protein coding gene Chr7:47089199-47090375 (+)
DBA/2J MGP_DBA2J_G0031947
protein coding gene Chr7:42363761-42364937 (+)
FVB/NJ MGP_FVBNJ_G0031908
protein coding gene Chr7:42083568-42084744 (+)
LP/J MGP_LPJ_G0032026
protein coding gene Chr7:44189686-44190864 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031944
protein coding gene Chr7:46039928-46041104 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032617
protein coding gene Chr7:43062714-43063890 (+)
PWK/PhJ MGP_PWKPhJ_G0030880
protein coding gene Chr7:35803329-35804505 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030719
protein coding gene Chr7:31113145-31114322 (+)
WSB/EiJ MGP_WSBEiJ_G0031273
protein coding gene Chr7:43605544-43606720 (+)



Homology
more
  • Human Ortholog
    NKG7, natural killer cell granule protein 7
  • Vertebrate Orthologs
    6
  • Human Ortholog
    NKG7, natural killer cell granule protein 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GIG1, GMP-17, p15-TIA-1
  • Links
    NCBI Gene ID: 4818
    neXtProt AC: NX_Q16617
    UniProt: Q16617

  • Chr Location
    19q13.41; chr19:51371616-51372706 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 72310 NCBI Gene Model | MGI Sequence Detail 1109 C57BL/6J ±  kb
transcript NM_024253 RefSeq | MGI Sequence Detail 813 C57BL/6  
polypeptide NP_077215 RefSeq | MGI Sequence Detail 165 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR004032 PMP-22/EMP/MP20
    IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919560
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory