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Sec61a2 Gene Detail
Summary
  • Symbol
    Sec61a2
  • Name
    Sec61, alpha subunit 2 (S. cerevisiae)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931071
    NCBI Gene: 57743
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:5870987-5895432 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 3.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931071
protein coding gene Chr2:5870977-5895432 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025326
protein coding gene Chr2:3004579-3028793 (-)
A/J MGP_AJ_G0025303
protein coding gene Chr2:2863638-2888179 (-)
AKR/J MGP_AKRJ_G0025271
protein coding gene Chr2:2947765-2973395 (-)
BALB/cJ MGP_BALBcJ_G0025299
protein coding gene Chr2:2842240-2866556 (-)
C3H/HeJ MGP_C3HHeJ_G0025059
protein coding gene Chr2:2906750-2930964 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025741
protein coding gene Chr2:3081622-3106962 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023155
protein coding gene Chr2:2673109-2697049 (-)
CAST/EiJ MGP_CASTEiJ_G0024522
protein coding gene Chr2:2949936-2974197 (-)
CBA/J MGP_CBAJ_G0025038
protein coding gene Chr2:3216927-3241141 (-)
DBA/2J MGP_DBA2J_G0025170
protein coding gene Chr2:2806894-2831108 (-)
FVB/NJ MGP_FVBNJ_G0025132
protein coding gene Chr2:2807012-2831171 (-)
LP/J MGP_LPJ_G0025256
protein coding gene Chr2:2950184-2974398 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025164
protein coding gene Chr2:3061903-3089948 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025799
protein coding gene Chr2:2941475-2965829 (-)
PWK/PhJ MGP_PWKPhJ_G0024273
protein coding gene Chr2:2801539-2825733 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024073
protein coding gene Chr2:2922649-2946878 (-)
WSB/EiJ MGP_WSBEiJ_G0024592
protein coding gene Chr2:2972757-3000544 (-)



Homology
more
  • Human Ortholog
    SEC61A2, Sec61 translocon alpha 2 subunit
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SEC61A2, Sec61 translocon alpha 2 subunit
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55176
    neXtProt AC: NX_Q9H9S3
    UniProt: Q9H9S3

  • Chr Location
    10p14; chr10:12129641-12169958 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025816 Ensembl Gene Model | MGI Sequence Detail 24446 C57BL/6J ±  kb
transcript ENSMUST00000102981 Ensembl | MGI Sequence Detail 2448 Not Applicable  
polypeptide ENSMUSP00000100046 Ensembl | MGI Sequence Detail 476 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory