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Ralgapa1
Gene Detail
Symbol

Name
ID
Ralgapa1
Ral GTPase activating protein, alpha subunit 1
MGI:1931050
Synonyms
2310003F20Rik, 4930400K19Rik, Garnl1, mKIAA0884, Tulip1
Feature Type
protein coding gene
Genetic Map
Chromosome 12
24.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:55602929-55821167 bp, - strand
From Ensembl annotation of GRCm38

  218239 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84805  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

HCOP human homology predictions: RALGAPA1
Gene Tree: Ralgapa1

Human
homologs
RALGAPA1, Ral GTPase activating protein, alpha subunit 1 (catalytic)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 253959
neXtProt AC: NX_Q6GYQ0

Human Synonyms: GARNL1, GRIPE, p240, RalGAPalpha1, TULIP1

Human Chr (Location): 14q13.2; chr14:35538352-35809304 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(10) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ralgapa1 interacts with 305 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process activation of GTPase activity, positive regulation of GTPase activity, ...
Component cytoplasm, nucleus
Function GTPase activator activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (21)    Tissues (21)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 6
Northern blot 15
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ralgapa1 ; ZFIN ralgapa1    NEW 
Molecular
reagents
All nucleic(14) cDNA(13) Other(1)
Microarray probesets(12)
Other database
links
Ensembl Gene Model ENSMUSG00000021027 (Evidence)
Entrez Gene 56784 (Evidence)
DoTS DT.101221026, DT.101737104, DT.525183, DT.531716, DT.55283212, DT.60101146, DT.91332980, DT.91334544, DT.91580794, DT.94259765
Consensus CDS Project CCDS36452.1
International Mouse Phenotyping Consortium Status Ralgapa1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021027 Ensembl Gene Model | MGI Sequence Detail 218239 C57BL/6J ±  kb
transcript ENSMUST00000110687 Ensembl | MGI Sequence Detail 7874 Not Applicable 
polypeptide ENSMUSP00000106315 Ensembl | MGI Sequence Detail 2035 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(23) UniProt(4)
Polymorphisms
SNPs within 2kb(557 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR000331 Rap GTPase activating protein domain
Protein Ontology PR:000030880 ral GTPase-activating protein subunit alpha-1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:1916733, MGI:1921051, MGI:2144861

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory