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Acp6 Gene Detail
Summary
  • Symbol
    Acp6
  • Name
    acid phosphatase 6, lysophosphatidic
  • Synonyms
    5730559A09Rik, ACPL1, mPACPL1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931010
    NCBI Gene: 66659
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:97066070-97083892 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 42.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931010
protein coding gene Chr3:97066070-97084615 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027638
protein coding gene Chr3:98076522-98095102 (+)
A/J MGP_AJ_G0027600
protein coding gene Chr3:94944278-94962796 (+)
AKR/J MGP_AKRJ_G0027567
protein coding gene Chr3:97214764-97233272 (+)
BALB/cJ MGP_BALBcJ_G0027610
protein coding gene Chr3:94754039-94776075 (+)
C3H/HeJ MGP_C3HHeJ_G0027342
protein coding gene Chr3:97493737-97512259 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028056
protein coding gene Chr3:101697526-101716082 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025397
protein coding gene Chr3:91180641-91199258 (+)
CAST/EiJ MGP_CASTEiJ_G0026797
protein coding gene Chr3:96755516-96774154 (+)
CBA/J MGP_CBAJ_G0027317
protein coding gene Chr3:105353586-105372105 (+)
DBA/2J MGP_DBA2J_G0027460
protein coding gene Chr3:94254084-94272636 (+)
FVB/NJ MGP_FVBNJ_G0027429
protein coding gene Chr3:92267416-92288258 (+)
LP/J MGP_LPJ_G0027565
protein coding gene Chr3:99346422-99365217 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027455
protein coding gene Chr3:111438843-111458366 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028110
protein coding gene Chr3:96809083-96828635 (+)
PWK/PhJ MGP_PWKPhJ_G0026522
protein coding gene Chr3:94102054-94120558 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026344
protein coding gene Chr3:95083215-95101989 (+)
WSB/EiJ MGP_WSBEiJ_G0026875
protein coding gene Chr3:97254592-97276234 (+)



Homology
more
  • Human Ortholog
    ACP6, acid phosphatase 6, lysophosphatidic
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACP6, acid phosphatase 6, lysophosphatidic
  • Synonyms
    ACPL1, LPAP, PACPL1
  • Links
    NCBI Gene ID: 51205
    neXtProt AC: NX_Q9NPH0
    UniProt: Q9NPH0

  • Chr Location
    1q21.2; chr1:147629652-147670524 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66659 NCBI Gene Model | MGI Sequence Detail 17823 C57BL/6J ±  kb
    transcript NM_019800 RefSeq | MGI Sequence Detail 1756 C57BL/6  
    polypeptide Q8BP40 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1913909, MGI:2139897
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 8
      Phenotypes 15
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory