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Fam181b Gene Detail
Summary
  • Symbol
    Fam181b
  • Name
    family with sequence similarity 181, member B
  • Synonyms
    A830059I20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930951
    NCBI Gene: 58238
Location & Maps
more
  • Sequence Map
    Chr7:93079865-93081867 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2003 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 51.66 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FAM181B, family with sequence similarity 181 member B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FAM181B, family with sequence similarity 181 member B
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 220382
    neXtProt AC: NX_A6NEQ2

  • Chr Location
    11q14.1; chr11:82732004-82733864 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    23 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Fam181b
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit normal fertility and morphology.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059838 VEGA Gene Model | MGI Sequence Detail 2003 C57BL/6J ±  kb
transcript OTTMUST00000146632 VEGA | MGI Sequence Detail 2003 Not Applicable  
polypeptide OTTMUSP00000076311 VEGA | MGI Sequence Detail 384 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    25 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR029359 FAM181
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 18
    Developmental Gene Expression 2
    Phenotypes 23
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:228526 Marks M, et al., Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene. 2016 Jan 10;575(2 Pt 2):438-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory