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Fam181b Gene Detail
Summary
  • Symbol
    Fam181b
  • Name
    family with sequence similarity 181, member B
  • Synonyms
    A830059I20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930951
    NCBI Gene: 58238
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:93079879-93081722 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 51.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930951
protein coding gene Chr7:93079865-93081867 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036466
pseudogene Chr7:95640545-95642376 (+)
A/J MGP_AJ_G0036452
pseudogene Chr7:93268680-93270511 (+)
AKR/J MGP_AKRJ_G0036402
pseudogene Chr7:95487986-95489817 (+)
BALB/cJ MGP_BALBcJ_G0036443
pseudogene Chr7:92921792-92923623 (+)
C3H/HeJ MGP_C3HHeJ_G0036135
pseudogene Chr7:95851648-95853479 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036955
pseudogene Chr7:99346545-99348380 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0034058
pseudogene Chr7:96020482-96022300 (+)
CAST/EiJ MGP_CASTEiJ_G0035328
pseudogene Chr7:87350725-87352560 (+)
CBA/J MGP_CBAJ_G0036107
pseudogene Chr7:102686369-102688200 (+)
DBA/2J MGP_DBA2J_G0036283
pseudogene Chr7:91686688-91688519 (+)
FVB/NJ MGP_FVBNJ_G0036238
pseudogene Chr7:91516881-91518712 (+)
LP/J MGP_LPJ_G0036334
pseudogene Chr7:96901776-96903607 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0036239
pseudogene Chr7:103824229-103826060 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0037067
pseudogene Chr7:94808105-94809936 (+)
PWK/PhJ MGP_PWKPhJ_G0035024
pseudogene Chr7:84758260-84760098 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034842
pseudogene Chr7:82103821-82105650 (+)
WSB/EiJ MGP_WSBEiJ_G0035523
pseudogene Chr7:95449923-95451762 (+)



Homology
more
  • Human Ortholog
    FAM181B, family with sequence similarity 181 member B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FAM181B, family with sequence similarity 181 member B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 220382
    neXtProt AC: NX_A6NEQ2
    UniProt: A6NEQ2

  • Chr Location
    11q14.1; chr11:82732004-82733864 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    23 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Fam181b
  • Incidental Mutations
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele exhibit normal fertility and morphology.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 58238 NCBI Gene Model | MGI Sequence Detail 1844 C57BL/6J ±  kb
transcript NM_021427 RefSeq | MGI Sequence Detail 1853 C57BL/6  
polypeptide Q80VF6 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR029359 FAM181
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Phenotypes 23
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:228526 Marks M, et al., Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene. 2016 Jan 10;575(2 Pt 2):438-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory