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Gar1 Gene Detail
Summary
  • Symbol
    Gar1
  • Name
    GAR1 ribonucleoprotein
  • Synonyms
    C430047J18Rik, GAR1, Nola1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930948
    NCBI Gene: 68147
Location & Maps
more
  • Sequence Map
    Chr3:129824912-129831396 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6485 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 59.16 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GAR1, GAR1 ribonucleoprotein
  • Human Ortholog
    GAR1, GAR1 ribonucleoprotein
    Orthology source: HGNC
  • Synonyms
    NOLA1
  • Links
    NCBI Gene ID: 54433
    neXtProt AC: NX_Q9NY12

  • Chr Location
    4q25; chr4:109815510-109824737 (+)  GRCh38.p2

  • HCOP
    human homology predictions: GAR1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Gene trapped
    14
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Gar1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028857 VEGA Gene Model | MGI Sequence Detail 6485 C57BL/6J ±  kb
transcript OTTMUST00000071463 VEGA | MGI Sequence Detail 1271 Not Applicable  
polypeptide OTTMUSP00000036621 VEGA | MGI Sequence Detail 231 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    129 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000007844 H/ACA ribonucleoprotein complex subunit 1
  • InterPro Domains
    IPR021154 H/ACA ribonucleoprotein complex, subunit Gar1
    IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1
    IPR009000 Translation protein, beta-barrel domain
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915397, MGI:2139572, MGI:2139683
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65787 Pogacic V, et al., Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. Mol Cell Biol. 2000 Dec;20(23):9028-40
  • Latest
    J:199000 Kappei D, et al., HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J. 2013 Jun 12;32(12):1681-701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory