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Scgb1b2 Gene Detail
Summary
  • Symbol
    Scgb1b2
  • Name
    secretoglobin, family 1B, member 2
  • Synonyms
    Abpa2, Abph, Apbh, lacrimal gland protein, LGP, Mja1l, Scgb1b1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930867
    NCBI Gene: 57426
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30989944-30991241 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.32 cM, cytoband B1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930867
 protein coding gene Chr7:30989944-30991246 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032064
 protein coding gene Chr7:30348085-30349387 (-)
A/J MGP_AJ_G0032042
 protein coding gene Chr7:29534009-29535311 (-)
AKR/J MGP_AKRJ_G0031975
 protein coding gene Chr7:30309226-30310528 (-)
BALB/cJ MGP_BALBcJ_G0032049
 protein coding gene Chr7:29727085-29728387 (-)
C3H/HeJ MGP_C3HHeJ_G0031766
 protein coding gene Chr7:30733216-30734518 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032515
 protein coding gene Chr7:31358181-31359483 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029564
 protein coding gene Chr7:30462860-30464167 (-)
CAST/EiJ MGP_CASTEiJ_G0031102
 protein coding gene Chr7:24004283-24005585 (-)
CBA/J MGP_CBAJ_G0031734
 protein coding gene Chr7:32834944-32836246 (-)
DBA/2J MGP_DBA2J_G0031886
 protein coding gene Chr7:29217162-29218464 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0031966
 protein coding gene Chr7:30692031-30693333 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031879
 protein coding gene Chr7:32053164-32054466 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032541
 protein coding gene Chr7:29751882-29753184 (-)
PWK/PhJ MGP_PWKPhJ_G0030823
 protein coding gene Chr7:24255363-24256665 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030660
 protein coding gene Chr7:20695724-20697026 (-)
WSB/EiJ MGP_WSBEiJ_G0031211
 protein coding gene Chr7:30239915-30241217 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57426 NCBI Gene Model | MGI Sequence Detail 1298 C57BL/6J ±  kb
transcript NM_020563 RefSeq | MGI Sequence Detail 425 Not Specified  
polypeptide NP_065588 RefSeq | MGI Sequence Detail 93 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR006178 Major allergen I polypeptide chain 1
    IPR016126 Secretoglobin
    IPR035960 Secretoglobin superfamily
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 1
  • Earliest
    J:82365 Reynolds SD, et al., Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Am J Respir Crit Care Med. 2002 Dec 1;166(11):1498-509
  • Latest
    J:239017 Steinmetz CC, et al., Upregulation of mu3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016 Sep 06;16(10):2711-22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory