About   Help   FAQ
Arid3b
Gene Detail
Symbol

Name
ID
Arid3b
AT rich interactive domain 3B (BRIGHT-like)
MGI:1930768
Synonyms
Bdp, Dri2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
31.56 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:57790353-57836793 bp, - strand
From VEGA annotation of GRCm38

  46441 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4721  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Arid3b

Human
homologs
Human Homolog ARID3B, AT rich interactive domain 3B (BRIGHT-like)
NCBI Gene ID 10620
neXtProt AC  NX_Q8IVW6
Human Synonyms  BDP, DRIL2
Human Chr (Location)  15q24; chr15:74541177-74598131 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(92) : Gene trapped(89) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele die before E11.5 displaying variable phenotypes associated with impaired generation of cranial-mesenchymal cells in the first and second branchial arches. Common defects include a wavy neural tube, small branchial arches, and a defective cardiovascular system.
 
Interactions
Arid3b interacts with 256 markers (Mir1b, Mir7-1, Mir7-2, ...)
Expression
Literature Summary: (11 records)
Data Summary: Results (178)    Tissues (155)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 170
RT-PCR 8
cDNA source data(65)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(66) cDNA(65) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000036791 (Evidence)
Ensembl Gene ModelENSMUSG00000004661 (Evidence)
Entrez Gene56380 (Evidence)
UniGene425588
DFCITC1580262, TC1590223
DoTSDT.103584981, DT.40134289, DT.486920, DT.91425505, DT.99695264
NIA Mouse Gene IndexU108385
Consensus CDS ProjectCCDS23233.1
International Mouse Knockout Project StatusArid3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036791 VEGA Gene Model | MGI Sequence Detail 46441 C57BL/6J ±  kb
transcript OTTMUST00000094427 VEGA | MGI Sequence Detail 4171 Not Applicable 
polypeptide OTTMUSP00000052509 VEGA | MGI Sequence Detail 568 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(172 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001606 ARID/BRIGHT DNA-binding domain
InterPro IPR023334 REKLES domain
Protein Ontology PR:000004266 AT-rich interactive domain-containing protein 3B
References
(Earliest) J:51742 Herrscher RF, et al., The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 1995 Dec 15;9(24):3067-82
(Latest) J:198566 Gurtan AM, et al., Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts. Genes Dev. 2013 Apr 15;27(8):941-54
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory