About   Help   FAQ
Ube2d2a Gene Detail
Summary
  • Symbol
    Ube2d2a
  • Name
    ubiquitin-conjugating enzyme E2D 2A
  • Synonyms
    1500034D03Rik, ubc4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930715
    NCBI Gene: 56550
  • Gene Overview
    MyGene.info: UBE2D2
Location & Maps
more
  • Sequence Map
    Chr18:35771559-35807172 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35614 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.24 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    UBE2D2, ubiquitin conjugating enzyme E2 D2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UBE2D2, ubiquitin conjugating enzyme E2 D2
    Orthology source: HomoloGene
  • Synonyms
    E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B
  • Links
    NCBI Gene ID: 7322
    neXtProt AC: NX_P62837

  • Chr Location
    5q31.2; chr5:139561166-139628434 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    24
  • Gene trapped
    23
  • Targeted
    1
  • Incidental Mutations
    APF
Homozygous null mice display a delay in testis maturation but have normal spermatogenesis, sperm motility, and fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56550 NCBI Gene Model | MGI Sequence Detail 35614 C57BL/6J ±  kb
transcript NM_019912 RefSeq | MGI Sequence Detail 2483 C57BL/6  
polypeptide P62838 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    179 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 242
    cDNA 242

    Microarray probesets 8
Other
Accession IDs
less
MGI:1919677
References
more
  • Summaries
    All 32
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:41090 Hatakeyama S, et al., Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases. J Biol Chem. 1997 Jun 13;272(24):15085-92
  • Latest
    J:194233 Starita LM, et al., Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):E1263-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/23/2016
MGI 6.05
The Jackson Laboratory