Zfp386
Gene Detail

Symbol Name ID

Zfp386 zinc finger protein 386 (Kruppel-like) MGI:1930708

Feature Type

protein coding gene

Genetic Map

Chromosome 12

62.59 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr12:116047724-116060592 bp, + strand From Ensembl annotation of GRCm38   12869 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:51668  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee

Protein SuperFamily: zinc finger protein ZFP-36
Gene Tree: Zfp386

Human homologs

Human Homolog		ZNF519, zinc finger protein 519
NCBI Gene ID		162655
neXtProt AC		NX_Q8TB69
Human Synonyms		HsT2362
Human Chr (Location)		18p11.21; chr18:14075989-14132489 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	negative regulation of transcription during meiosis
Component	cellular_component
Function	chromatin binding, DNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (92)    Tissues (71)    Images (30)
Theiler Stages: 2, 3, 4, 5, 11, 13, 17, 21, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	77
RT-PCR	15

cDNA source data(66)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(68) cDNA(67) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000042063 (Evidence)
Entrez Gene	56220 (Evidence)
UniGene	254997
DFCI	TC1579897, TC1581541, TC1601539, TC1613912, TC1685244
DoTS	DT.101300018, DT.485841, DT.55212161, DT.91363961, DT.91578701
NIA Mouse Gene Index	U043316, U060268
Consensus CDS Project	CCDS26209.1
International Mouse Knockout Project Status	Zfp386

Sequences

Length	Strain/Species
genomic	ENSMUSG00000042063	Ensembl Gene Model | MGI Sequence Detail	12869	C57BL/6J
transcript	ENSMUST00000073551	Ensembl | MGI Sequence Detail	2063	Not Applicable
polypeptide	ENSMUSP00000073241	Ensembl | MGI Sequence Detail	626	Not Applicable

All sequences(37) RefSeq(4) UniProt(5)

Polymorphisms

SNPs(197 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001909	Krueppel-associated box
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)