About   Help   FAQ
Higd1a Gene Detail
Summary
  • Symbol
    Higd1a
  • Name
    HIG1 domain family, member 1A
  • Synonyms
    2210020B17Rik, 7420700H20Rik, Hig1, HIMP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930666
    NCBI Gene: 56295
  • Gene Overview
    MyGene.info: HIGD1A
Location & Maps
more
  • Sequence Map
    Chr9:121848560-121858000 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9441 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 72.67 cM, cytoband F4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    HIGD1A, HIG1 hypoxia inducible domain family member 1A
  • Vertebrate Orthologs
    19
  • Human Ortholog
    HIGD1A, HIG1 hypoxia inducible domain family member 1A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HIG1, RCF1a
  • Links
    NCBI Gene ID: 25994
    neXtProt AC: NX_Q9Y241

  • Chr Location
    3p22.1; chr3:42782908-42804535 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    10
  • Gene trapped
    8
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038412 Ensembl Gene Model | MGI Sequence Detail 9441 C57BL/6J ±  kb
transcript ENSMUST00000060251 Ensembl | MGI Sequence Detail 1873 Not Applicable  
polypeptide ENSMUSP00000054881 Ensembl | MGI Sequence Detail 95 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    71 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031505 HIG1 domain family member 1A
  • InterPro Domains
    IPR007667 Hypoxia induced protein, domain
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 6
Other
Accession IDs
less
MGI:1914052, MGI:1917640, MGI:2143007, MGI:2143283
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:222038 Ameri K, et al., HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Rep. 2015 Feb 12;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory