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Osbpl5 Gene Detail
Summary
  • Symbol
    Osbpl5
  • Name
    oxysterol binding protein-like 5
  • Synonyms
    1110006M06Rik, Obph1, ORP5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930265
    NCBI Gene: 79196
  • Gene Overview
    MyGene.info: OSBPL5
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:143688762-143756980 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 88.29 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    504 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930265
protein coding gene Chr7:143688762-143756985 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033280
protein coding gene Chr7:149015550-149084460 (-)
A/J MGP_AJ_G0033263
protein coding gene Chr7:144685080-144753789 (-)
AKR/J MGP_AKRJ_G0033194
protein coding gene Chr7:148761915-148829808 (-)
BALB/cJ MGP_BALBcJ_G0033263
protein coding gene Chr7:144475756-144545229 (-)
C3H/HeJ MGP_C3HHeJ_G0032977
protein coding gene Chr7:148510016-148590759 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033773
protein coding gene Chr7:154412065-154483500 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030746
protein coding gene Chr7:145853145-145922920 (-)
CAST/EiJ MGP_CASTEiJ_G0032300
protein coding gene Chr7:140837559-140905812 (-)
CBA/J MGP_CBAJ_G0032950
protein coding gene Chr7:159651160-159721326 (-)
DBA/2J MGP_DBA2J_G0033104
protein coding gene Chr7:142669006-142736993 (-)
FVB/NJ MGP_FVBNJ_G0033052
protein coding gene Chr7:142604697-142681242 (-)
LP/J MGP_LPJ_G0033196
protein coding gene Chr7:150555470-150625286 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033086
protein coding gene Chr7:160258193-160330672 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033791
protein coding gene Chr7:147714738-147786771 (-)
PWK/PhJ MGP_PWKPhJ_G0032010
protein coding gene Chr7:135969970-136043104 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031854
protein coding gene Chr7:134521362-134591216 (-)
WSB/EiJ MGP_WSBEiJ_G0032413
protein coding gene Chr7:148714531-148785163 (-)



Homology
more
  • Human Ortholog
    OSBPL5, oxysterol binding protein like 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    OSBPL5, oxysterol binding protein like 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    OBPH1, ORP5
  • Links
    NCBI Gene ID: 114879
    neXtProt AC: NX_Q9H0X9
    UniProt: Q9H0X9

  • Chr Location
    11p15.4; chr11:3087116-3165352 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 79196 NCBI Gene Model | MGI Sequence Detail 68219 C57BL/6J ±  kb
transcript NM_024289 RefSeq | MGI Sequence Detail 3994 C57BL/6  
polypeptide Q9ER64 UniProt | EBI | MGI Sequence Detail 874 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000648 Oxysterol-binding protein
    IPR018494 Oxysterol-binding protein, conserved site
    IPR037239 Oxysterol-binding protein superfamily
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
Molecular
Reagents
less
  • All nucleic 44
    cDNA 37
    Primer pair 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915711, MGI:2141974
References
more
  • Summaries
    All 51
    Developmental Gene Expression 18
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:10529 Bastian H, et al., A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]. EMBO J. 1990 Jun;9(6):1839-52
  • Latest
    J:236096 Tremblay MG, et al., Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility. Cell Cycle. 2016 Sep;15(17):2360-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory