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Wdr6 Gene Detail
Summary
  • Symbol
    Wdr6
  • Name
    WD repeat domain 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930140
    NCBI Gene: 83669
  • Gene Overview
    MyGene.info: WDR6
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108572313-108578670 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.51 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930140
protein coding gene Chr9:108572311-108578739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035307
protein coding gene Chr9:110539677-110546101 (-)
A/J MGP_AJ_G0035286
protein coding gene Chr9:106488544-106494967 (-)
AKR/J MGP_AKRJ_G0035218
protein coding gene Chr9:109157638-109164061 (-)
BALB/cJ MGP_BALBcJ_G0035280
protein coding gene Chr9:106184008-106190431 (-)
C3H/HeJ MGP_C3HHeJ_G0034990
protein coding gene Chr9:109558986-109565409 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035800
protein coding gene Chr9:113554360-113560788 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032698
protein coding gene Chr9:103916696-103923156 (-)
CAST/EiJ MGP_CASTEiJ_G0034301
protein coding gene Chr9:109516962-109523406 (-)
CBA/J MGP_CBAJ_G0034958
protein coding gene Chr9:117560559-117566976 (-)
DBA/2J MGP_DBA2J_G0035119
protein coding gene Chr9:105947509-105953932 (-)
FVB/NJ MGP_FVBNJ_G0035067
protein coding gene Chr9:104709176-104715599 (-)
LP/J MGP_LPJ_G0035195
protein coding gene Chr9:110734227-110740678 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035106
protein coding gene Chr9:119132661-119139084 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035821
protein coding gene Chr9:109436433-109442856 (-)
PWK/PhJ MGP_PWKPhJ_G0034008
protein coding gene Chr9:106272946-106279412 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033843
protein coding gene Chr9:109499123-109505541 (-)
WSB/EiJ MGP_WSBEiJ_G0034422
protein coding gene Chr9:109318167-109324593 (-)



Homology
more
  • Human Ortholog
    WDR6, WD repeat domain 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDR6, WD repeat domain 6
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 11180
    neXtProt AC: NX_Q9NNW5
    UniProt: Q9NNW5

  • Chr Location
    3p21.31; chr3:49007062-49015953 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 117682
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WDR6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 83669 NCBI Gene Model | MGI Sequence Detail 6358 C57BL/6J ±  kb
transcript NM_031392 RefSeq | MGI Sequence Detail 4137 C57BL/6  
polypeptide Q99ME2 UniProt | EBI | MGI Sequence Detail 1125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory