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Prdm15 Gene Detail
Summary
  • Symbol
    Prdm15
  • Name
    PR domain containing 15
  • Synonyms
    E130018M06Rik, Zfp298
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930121
    NCBI Gene: 114604
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:97791467-97851850 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 57.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930121
protein coding gene Chr16:97791467-97852100 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023094
protein coding gene Chr16:99241620-99307190 (-)
A/J MGP_AJ_G0023062
protein coding gene Chr16:94557036-94618137 (-)
AKR/J MGP_AKRJ_G0023032
protein coding gene Chr16:97478209-97541943 (-)
BALB/cJ MGP_BALBcJ_G0023064
protein coding gene Chr16:95105506-95167559 (-)
C3H/HeJ MGP_C3HHeJ_G0022825
protein coding gene Chr16:97990419-98055327 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023511
protein coding gene Chr16:102336847-102402036 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021012
protein coding gene Chr16:92385270-92445764 (-)
CAST/EiJ MGP_CASTEiJ_G0022345
protein coding gene Chr16:98804745-98868408 (-)
CBA/J MGP_CBAJ_G0022794
protein coding gene Chr16:106784306-106854611 (-)
DBA/2J MGP_DBA2J_G0022928
protein coding gene Chr16:94416383-94477115 (-)
FVB/NJ MGP_FVBNJ_G0022902
protein coding gene Chr16:93575702-93636717 (-)
LP/J MGP_LPJ_G0022998
protein coding gene Chr16:98890272-98953203 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022923
protein coding gene Chr16:110928060-110993681 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023529
protein coding gene Chr16:98008584-98070173 (-)
PWK/PhJ MGP_PWKPhJ_G0022089
protein coding gene Chr16:94751726-94812222 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021919
protein coding gene Chr16:97508624-97572379 (-)
WSB/EiJ MGP_WSBEiJ_G0022395
protein coding gene Chr16:98290945-98352163 (-)



Homology
more
  • Human Ortholog
    PRDM15, PR/SET domain 15
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRDM15, PR/SET domain 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C21orf83, PFM15, ZNF298
  • Links
    NCBI Gene ID: 63977
    neXtProt AC: NX_P57071
    UniProt: P57071

  • Chr Location
    21q22.3; chr21:41798225-41879482 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 56941
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PRDM15
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000014039 Ensembl Gene Model | MGI Sequence Detail 60384 C57BL/6J ±  kb
transcript ENSMUST00000095849 Ensembl | MGI Sequence Detail 6346 Not Applicable  
polypeptide ENSMUSP00000093533 Ensembl | MGI Sequence Detail 1174 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 51
    Primer pair 4

    Microarray probesets 4
Other
Accession IDs
less
MGI:2181988, MGI:2442747
References
more
  • Summaries
    All 42
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:69673 Davisson MT, et al., Evolutionary breakpoints on human chromosome 21. Genomics. 2001 Nov;78(1/2):99-106
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory