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Tfip11 Gene Detail
Summary
  • Symbol
    Tfip11
  • Name
    tuftelin interacting protein 11
  • Synonyms
    Tip39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930075
    NCBI Gene: 54723
  • Gene Overview
    MyGene.info: TFIP11
Location & Maps
more
  • Sequence Map
    Chr5:112326358-112338073 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11716 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 54.69 cM, cytoband F
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TFIP11, tuftelin interacting protein 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TFIP11, tuftelin interacting protein 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bK445C9.6, hNtr1, NTR1, Spp382, TIP39
  • Links
    NCBI Gene ID: 24144
    neXtProt AC: NX_Q9UBB9

  • Chr Location
    22q12.1; chr22:26491927-26512496 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Tfip11
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023449 VEGA Gene Model | MGI Sequence Detail 11716 C57BL/6J ±  kb
transcript OTTMUST00000057013 VEGA | MGI Sequence Detail 3560 Not Applicable  
polypeptide OTTMUSP00000027457 VEGA | MGI Sequence Detail 838 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    66 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000016278 tuftelin-interacting protein 11
  • InterPro Domains
    IPR022783 GC-rich sequence DNA-binding factor domain
    IPR000467 G-patch domain
    IPR024933 Septin and tuftelin interacting protein
    IPR022159 Tuftelin interacting protein, N-terminal domain
Molecular
Reagents
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  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGI:2140799, MGI:2141127
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:51772 Paine CT, et al., Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system. Connect Tissue Res. 1998;39(1-3):257-267
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory