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Psors1c2 Gene Detail
Summary
  • Symbol
    Psors1c2
  • Name
    psoriasis susceptibility 1 candidate 2 (human)
  • Synonyms
    Pcg, SPR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930025
    NCBI Gene: 57390
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35533201-35534647 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930025
protein coding gene Chr17:35533201-35534647 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023643
protein coding gene Chr17:35705167-35706613 (+)
A/J MGP_AJ_G0023598
protein coding gene Chr17:34605498-34606944 (+)
AKR/J MGP_AKRJ_G0023568
protein coding gene Chr17:35011380-35012826 (+)
BALB/cJ MGP_BALBcJ_G0023603
protein coding gene Chr17:34733288-34734734 (+)
C3H/HeJ MGP_C3HHeJ_G0023369
protein coding gene Chr17:35476856-35478302 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024045
protein coding gene Chr17:37166615-37168061 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021523
protein coding gene Chr17:32305079-32306542 (+)
CAST/EiJ MGP_CASTEiJ_G0022860
protein coding gene Chr17:35579945-35581390 (+)
CBA/J MGP_CBAJ_G0023347
protein coding gene Chr17:38710789-38712235 (+)
DBA/2J MGP_DBA2J_G0023471
protein coding gene Chr17:33918565-33920011 (+)
FVB/NJ MGP_FVBNJ_G0023442
protein coding gene Chr17:33710340-33711786 (+)
LP/J MGP_LPJ_G0023551
protein coding gene Chr17:36089571-36091017 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023463
protein coding gene Chr17:37524518-37525964 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024088
protein coding gene Chr17:35343918-35345364 (+)
PWK/PhJ MGP_PWKPhJ_G0022611
protein coding gene Chr17:32772321-32773767 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022430
protein coding gene Chr17:33381032-33382478 (+)
WSB/EiJ MGP_WSBEiJ_G0022926
protein coding gene Chr17:35476556-35478002 (+)



Homology
more
  • Human Ortholog
    PSORS1C2, psoriasis susceptibility 1 candidate 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PSORS1C2, psoriasis susceptibility 1 candidate 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf17, SPR1
  • Links
    NCBI Gene ID: 170680
    neXtProt AC: NX_Q9UIG4
    UniProt: Q9UIG4

  • Chr Location
    6p21.33; chr6:31137534-31139350 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57390 NCBI Gene Model | MGI Sequence Detail 1447 C57BL/6J ±  kb
transcript NM_020576 RefSeq | MGI Sequence Detail 850 C57BL/6  
polypeptide Q80ZC9 UniProt | EBI | MGI Sequence Detail 134 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013402 psoriasis susceptibility 1 candidate gene 2 protein
  • InterPro Domains
    IPR029271 Psoriasis susceptibility 1 candidate gene 2 protein
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146861
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:78525 Lemon WJ, et al., Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays. J Med Genet. 2002 Sep;39(9):644-55
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory