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Klk11 Gene Detail
Summary
  • Symbol
    Klk11
  • Name
    kallikrein related-peptidase 11
  • Synonyms
    2310015I08Rik, hippostasin, Prss20, TLSP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929977
    NCBI Gene: 56538
  • Gene Overview
    MyGene.info: KLK11
Location & Maps
more
  • Sequence Map
    Chr7:43774604-43779263 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4660 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KLK11, kallikrein related peptidase 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KLK11, kallikrein related peptidase 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PRSS20, TLSP
  • Links
    NCBI Gene ID: 11012
    neXtProt AC: NX_Q9UBX7

  • Chr Location
    19q13.33; chr19:51022231-51028034 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058308 VEGA Gene Model | MGI Sequence Detail 4660 C57BL/6J ±  kb
transcript OTTMUST00000143188 VEGA | MGI Sequence Detail 1312 Not Applicable  
polypeptide OTTMUSP00000074657 VEGA | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    86 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000009408 kallikrein-11
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1913805
References
more
  • Summaries
    All 23
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65795 Mitsui S, et al., cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20)(1). Biochim Biophys Acta. 2000 Nov 15;1494(1-2):206-10
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory