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Klk11 Gene Detail
Summary
  • Symbol
    Klk11
  • Name
    kallikrein related-peptidase 11
  • Synonyms
    2310015I08Rik, hippostasin, Prss20, TLSP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929977
    NCBI Gene: 56538
Location & Maps
more
  • Sequence Map
    Chr7:43774617-43779258 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4642 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    KLK11, kallikrein related peptidase 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KLK11, kallikrein related peptidase 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PRSS20, TLSP
  • Links
    NCBI Gene ID: 11012
    neXtProt AC: NX_Q9UBX7

  • Chr Location
    19q13.33; chr19:51022231-51028034 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067616 Ensembl Gene Model | MGI Sequence Detail 4642 C57BL/6J ±  kb
transcript ENSMUST00000080211 Ensembl | MGI Sequence Detail 1294 Not Applicable  
polypeptide ENSMUSP00000079101 Ensembl | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    97 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1913805
References
more
  • Summaries
    All 23
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65795 Mitsui S, et al., cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20)(1). Biochim Biophys Acta. 2000 Nov 15;1494(1-2):206-10
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory