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Klk11
Gene Detail
 Symbol
Name
ID
Klk11
kallikrein related-peptidase 11
MGI:1929977
Synonyms 2310015I08Rik, hippostasin, Prss20, TLSP
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:43774617-43779258 bp, + strand
From Ensembl annotation of GRCm38

  4642 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27048  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Klk11

Human
homologs
Human Homolog KLK11, kallikrein-related peptidase 11
NCBI Gene ID 11012
neXtProt AC  NX_Q9UBX7
Human Synonyms  PRSS20, TLSP
Human Chr (Location)  19q13.33; chr19:51022231-51028034 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(10)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(11) cDNA(10) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000067616 (Evidence)
Entrez Gene56538 (Evidence)
UniGene154276
DFCITC1586339
DoTSDT.50316147, DT.91338283
NIA Mouse Gene IndexU267856
EC3.4.21.-
Consensus CDS ProjectCCDS39935.1, CCDS52227.1
International Mouse Knockout Project StatusKlk11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067616 Ensembl Gene Model | MGI Sequence Detail 4642 C57BL/6J ±  kb
transcript ENSMUST00000080211 Ensembl | MGI Sequence Detail 1294 Not Applicable 
polypeptide ENSMUSP00000079101 Ensembl | MGI Sequence Detail 276 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009408 kallikrein-11
References (Earliest) J:65795 Mitsui S, et al., cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20)(1). Biochim Biophys Acta. 2000 Nov 15;1494(1-2):206-10
(Latest) J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All references(26)
Other
accession IDs
MGI:1913805

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory