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Tssk3 Gene Detail
Summary
  • Symbol
    Tssk3
  • Name
    testis-specific serine kinase 3
  • Synonyms
    1700014N07Rik, 4930594I21Rik, Stk22c, Stk22d, Tssk-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929914
    NCBI Gene: 58864
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129489008-129490770 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.26 cM, cytoband D2.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    30 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929914
protein coding gene Chr4:129489008-129491022 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028824
protein coding gene Chr4:131412363-131414371 (-)
A/J MGP_AJ_G0028783
protein coding gene Chr4:126167628-126169636 (-)
AKR/J MGP_AKRJ_G0028736
protein coding gene Chr4:129673681-129675689 (-)
BALB/cJ MGP_BALBcJ_G0028806
protein coding gene Chr4:126762824-126764832 (-)
C3H/HeJ MGP_C3HHeJ_G0028520
protein coding gene Chr4:129738179-129740187 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029248
protein coding gene Chr4:136355642-136357650 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026521
protein coding gene Chr4:119298515-119300526 (-)
CAST/EiJ MGP_CASTEiJ_G0027953
protein coding gene Chr4:127911811-127914464 (-)
CBA/J MGP_CBAJ_G0028486
protein coding gene Chr4:139728249-139730257 (-)
DBA/2J MGP_DBA2J_G0028635
protein coding gene Chr4:126599712-126601720 (-)
FVB/NJ MGP_FVBNJ_G0028602
protein coding gene Chr4:125360591-125362599 (-)
LP/J MGP_LPJ_G0028736
protein coding gene Chr4:131689584-131691592 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028628
protein coding gene Chr4:144570079-144572069 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029286
protein coding gene Chr4:130051745-130053753 (-)
PWK/PhJ MGP_PWKPhJ_G0027674
protein coding gene Chr4:123194748-123197443 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027501
protein coding gene Chr4:125917215-125919221 (-)
WSB/EiJ MGP_WSBEiJ_G0028033
protein coding gene Chr4:130170730-130172738 (-)



Homology
more
  • Human Ortholog
    TSSK3, testis specific serine kinase 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TSSK3, testis specific serine kinase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPOGA3, STK22C, STK22D, TSK3
  • Links
    NCBI Gene ID: 81629
    neXtProt AC: NX_Q96PN8
    UniProt: Q96PN8

  • Chr Location
    1p35.1; chr1:32362261-32364325 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Tssk3
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 58864 NCBI Gene Model | MGI Sequence Detail 1763 C57BL/6J ±  kb
transcript NM_080442 RefSeq | MGI Sequence Detail 1034 C57BL/6  
polypeptide Q9D2E1 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916640, MGI:1925477, MGI:2148928
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:62058 Zuercher G, et al., A novel member of the testis specific serine kinase family, tssk-3, expressed in the leydig cells of sexually mature mice. Mech Dev. 2000 May;93(1-2):175-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory