Cend1
Gene Detail

Symbol Name ID

Cend1 cell cycle exit and neuronal differentiation 1 MGI:1929898

Synonyms

1500001H12Rik, BM88

Feature Type

protein coding gene

Genetic Map

Chromosome 7

86.77 cM, cytoband F5
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:141426446-141429491 bp, - strand From VEGA annotation of GRCm38   3046 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9566  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Cend1

Human homologs

Human Homolog		CEND1, cell cycle exit and neuronal differentiation 1
NCBI Gene ID		51286
neXtProt AC		NX_Q8N111
Human Synonyms		BM88
Human Chr (Location)		11p15.5; chr11:787110-790126 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Mice homozygous for a null mutation display impaired cerebellar development with defects in granule cell proliferation and migration and purkinje cell arborization. These defects result in a thin cerebellar molecular layer and impaired coordination in adults.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	adult walking behavior, cerebellar granular layer maturation, ...
Component	integral to membrane, membrane
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (288)    Tissues (35)    Images (68)
Theiler Stages: 20, 21, 23

Assay Type	Results
Immunohistochemistry	14
RNA in situ	272
RT-PCR	2

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) cDNA(24) Primer pair(1)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000034077 (Evidence)
Ensembl Gene Model	ENSMUSG00000060240 (Evidence)
Entrez Gene	57754 (Evidence)
UniGene	87027
DFCI	TC1577449
DoTS	DT.101378190, DT.487159, DT.94399869, DT.97333110
NIA Mouse Gene Index	U029457
Consensus CDS Project	CCDS22012.1
International Mouse Knockout Project Status	Cend1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000034077	VEGA Gene Model | MGI Sequence Detail	3046	C57BL/6J
transcript	OTTMUST00000086112	VEGA | MGI Sequence Detail	1697	Not Applicable
polypeptide	OTTMUSP00000046570	VEGA | MGI Sequence Detail	149	Not Applicable

All sequences(34) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(15 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR020162	Cell cycle exit/neuronal differentiation protein 1
Protein Ontology	PR:000005322	cell cycle exit and neuronal differentiation protein 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)

Other accession IDs

MGI:1916208, MGI:2141931