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As3mt Gene Detail
Summary
  • Symbol
    As3mt
  • Name
    arsenic (+3 oxidation state) methyltransferase
  • Synonyms
    2310045H08Rik, Cyt19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929882
    NCBI Gene: 57344
  • Gene Overview
    MyGene.info: AS3MT
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46707443-46741095 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.97 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929882
protein coding gene Chr19:46707359-46741099 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025216
protein coding gene Chr19:46462920-46499173 (+)
A/J MGP_AJ_G0025192
protein coding gene Chr19:44133122-44166883 (+)
AKR/J MGP_AKRJ_G0025161
protein coding gene Chr19:45570036-45606477 (+)
BALB/cJ MGP_BALBcJ_G0025187
protein coding gene Chr19:44187033-44221696 (+)
C3H/HeJ MGP_C3HHeJ_G0024947
protein coding gene Chr19:45750515-45788768 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025630
protein coding gene Chr19:47573666-47615668 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023044
protein coding gene Chr19:43373372-43406988 (+)
CAST/EiJ MGP_CASTEiJ_G0024412
protein coding gene Chr19:45568806-45607933 (+)
CBA/J MGP_CBAJ_G0024927
protein coding gene Chr19:49969310-50013067 (+)
DBA/2J MGP_DBA2J_G0025059
protein coding gene Chr19:43953351-43985840 (+)
FVB/NJ MGP_FVBNJ_G0025020
protein coding gene Chr19:43739528-43776760 (+)
LP/J MGP_LPJ_G0025145
protein coding gene Chr19:46344512-46384986 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025051
protein coding gene Chr19:49302460-49344661 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025688
protein coding gene Chr19:45688909-45724854 (+)
PWK/PhJ MGP_PWKPhJ_G0024161
protein coding gene Chr19:43909549-43943860 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023965
protein coding gene Chr19:44336849-44377584 (+)
WSB/EiJ MGP_WSBEiJ_G0024482
protein coding gene Chr19:45836652-45879239 (+)



Homology
more
  • Human Ortholog
    AS3MT, arsenite methyltransferase
  • Vertebrate Orthologs
    12
  • Human Ortholog
    AS3MT, arsenite methyltransferase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CYT19
  • Links
    NCBI Gene ID: 57412
    neXtProt AC: NX_Q9HBK9
    UniProt: Q9HBK9

  • Chr Location
    10q24.32; chr10:102869453-102901899 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have abnormalities in arsenic methylation and in the distribution/retention of orally administered arsenate.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003559 Ensembl Gene Model | MGI Sequence Detail 33653 C57BL/6J ±  kb
transcript ENSMUST00000003655 Ensembl | MGI Sequence Detail 1751 Not Applicable  
polypeptide ENSMUSP00000003655 Ensembl | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913858
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:199302 Veenvliet JV, et al., Specification of dopaminergic subsets involves interplay of En1 and Pitx3. Development. 2013 Aug;140(16):3373-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory