Mogs
Gene Detail

Symbol Name ID

Mogs mannosyl-oligosaccharide glucosidase MGI:1929872

Synonyms

1810017N02Rik, Gcs1

Feature Type

protein coding gene

Genetic Map

Chromosome 6

35.94 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr6:83115496-83118898 bp, + strand From VEGA annotation of GRCm38   3403 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4593  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: mannosyl-oligosaccharide glucosidase
Gene Tree: Mogs

Human homologs

Human Homolog		MOGS, mannosyl-oligosaccharide glucosidase
NCBI Gene ID		7841
neXtProt AC		NX_Q13724
Human Synonyms		CDG2B, CWH41, DER7, GCS1
Human Chr (Location)		2p13.1; chr2:74688184-74692537 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MOGS

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	metabolic process, oligosaccharide metabolic process
Component	endoplasmic reticulum, integral to membrane, ...
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (3)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(110)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(111) cDNA(110) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000024275 (Evidence)
Ensembl Gene Model	ENSMUSG00000030036 (Evidence)
Entrez Gene	57377 (Evidence)
UniGene	28188
DFCI	TC1575242
DoTS	DT.40134981, DT.533926
NIA Mouse Gene Index	U007077
EC	3.2.1.106
Consensus CDS Project	CCDS20273.1
International Mouse Knockout Project Status	Mogs

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024275	VEGA Gene Model | MGI Sequence Detail	3403	C57BL/6J
transcript	OTTMUST00000059442	VEGA | MGI Sequence Detail	2780	Not Applicable
polypeptide	OTTMUSP00000028911	VEGA | MGI Sequence Detail	834	Not Applicable

All sequences(41) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(3 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004888	Glycoside hydrolase, family 63
InterPro	IPR008928	Six-hairpin glycosidase-like
Protein Ontology	PR:000010518	mannosyl-oligosaccharide glucosidase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
All references(35)

Other accession IDs

MGI:1353639, MGI:1916290