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Mogs
Gene Detail
Symbol

Name
ID
Mogs
mannosyl-oligosaccharide glucosidase
MGI:1929872
Synonyms
1810017N02Rik, Gcs1
Feature Type
protein coding gene
Genetic Map
Chromosome 6
35.94 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:83115496-83118898 bp, + strand
From VEGA annotation of GRCm38

  3403 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4593  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: MOGS
Protein SuperFamily: mannosyl-oligosaccharide glucosidase
Gene Tree: Mogs

Human
homologs
MOGS, mannosyl-oligosaccharide glucosidase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7841
neXtProt AC: NX_Q13724

Human Synonyms: CDG2B, CWH41, DER7, GCS1

Human Chr (Location): 2p13.1; chr2:74461057-74465410 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MOGS

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Spontaneous(1) Targeted(2)
Genomic Mutations involving Mogs (1)
Incidental mutations (data from APF , CvDC )
Interactions
Mogs interacts with 37 markers (Mir22, Mir27b, Mir30b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process metabolic process, oligosaccharide metabolic process, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(111)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mogs ; ZFIN mogs    NEW 
Molecular
reagents
All nucleic(112) cDNA(111) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000024275 (Evidence)
Ensembl Gene Model ENSMUSG00000030036 (Evidence)
Entrez Gene 57377 (Evidence)
UniGene 28188
DFCI TC1575242
DoTS DT.40134981, DT.533926
NIA Mouse Gene Index U007077
EC 3.2.1.106
Consensus CDS Project CCDS20273.1
International Mouse Phenotyping Consortium Status Mogs
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024275 VEGA Gene Model | MGI Sequence Detail 3403 C57BL/6J ±  kb
transcript OTTMUST00000059442 VEGA | MGI Sequence Detail 2780 Not Applicable 
polypeptide OTTMUSP00000028911 VEGA | MGI Sequence Detail 834 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(7 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004888 Glycoside hydrolase, family 63
InterPro IPR008928 Six-hairpin glycosidase-like
Protein Ontology PR:000010518 mannosyl-oligosaccharide glucosidase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
All references(34)
Other
accession IDs
MGI:1353639, MGI:1916290

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory