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Rgs20 Gene Detail
Summary
  • Symbol
    Rgs20
  • Name
    regulator of G-protein signaling 20
  • Synonyms
    2900073E09Rik, Rgsz1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929866
    NCBI Gene: 58175
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:4979799-5140508 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 1.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    962 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929866
protein coding gene Chr1:4976342-5140528 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015814
protein coding gene Chr1:1949453-2111778 (-)
A/J MGP_AJ_G0015796
protein coding gene Chr1:2028311-2204578 (-)
AKR/J MGP_AKRJ_G0015755
protein coding gene Chr1:2011340-2176705 (-)
BALB/cJ MGP_BALBcJ_G0015752
protein coding gene Chr1:1954957-2118299 (-)
C3H/HeJ MGP_C3HHeJ_G0015586
protein coding gene Chr1:1987593-2159347 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016204
protein coding gene Chr1:2066129-2233095 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013926
protein coding gene Chr1:1691863-1834231 (-)
CAST/EiJ MGP_CASTEiJ_G0015166
protein coding gene Chr1:2170302-2349691 (-)
CBA/J MGP_CBAJ_G0015560
protein coding gene Chr1:2180980-2389517 (-)
DBA/2J MGP_DBA2J_G0015658
protein coding gene Chr1:1936045-2112215 (-)
FVB/NJ MGP_FVBNJ_G0015663
protein coding gene Chr1:1905232-2071611 (-)
LP/J MGP_LPJ_G0015731
protein coding gene Chr1:2134302-2300292 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015682
protein coding gene Chr1:2342220-2550779 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016251
protein coding gene Chr1:1972265-2137695 (-)
PWK/PhJ MGP_PWKPhJ_G0014950
protein coding gene Chr1:1868796-2034429 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014730
protein coding gene Chr1:2145052-2318078 (-)
WSB/EiJ MGP_WSBEiJ_G0015230
protein coding gene Chr1:1968263-2140697 (-)



Homology
more
  • Human Ortholog
    RGS20, regulator of G protein signaling 20
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RGS20, regulator of G protein signaling 20
  • Synonyms
    g(z)GAP, gz-GAP, RGSZ1, ZGAP1
  • Links
    NCBI Gene ID: 8601
    neXtProt AC: NX_O76081
    UniProt: O76081

  • Chr Location
    8q11.23; chr8:53851795-53959303 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002459 Ensembl Gene Model | MGI Sequence Detail 160710 C57BL/6J ±  kb
transcript ENSMUST00000118000 Ensembl | MGI Sequence Detail 2125 Not Applicable  
polypeptide ENSMUSP00000113398 Ensembl | MGI Sequence Detail 372 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920256
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345521 Sakloth F, et al., A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward. Mol Pharmacol. 2023 Jan;103(1):1-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory