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Myg1 Gene Detail
Summary
  • Symbol
    Myg1
  • Name
    melanocyte proliferating gene 1
  • Synonyms
    0610023A07Rik, 2810433J21Rik, 5830429P19Rik, Gamm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929864
    NCBI Gene: 60315
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102240144-102246574 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    60 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929864
 protein coding gene Chr15:102240144-102246574 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022409
 protein coding gene Chr15:104502520-104509164 (+)
A/J MGP_AJ_G0022371
 protein coding gene Chr15:100391770-100398255 (+)
AKR/J MGP_AKRJ_G0022346
 protein coding gene Chr15:103434847-103441931 (+)
BALB/cJ MGP_BALBcJ_G0022375
 protein coding gene Chr15:100437469-100443899 (+)
C3H/HeJ MGP_C3HHeJ_G0022142
 protein coding gene Chr15:103507882-103514367 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022824
 protein coding gene Chr15:108386619-108393049 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020347
 protein coding gene Chr15:96165949-96172244 (+)
CAST/EiJ MGP_CASTEiJ_G0021668
 protein coding gene Chr15:104379351-104386666 (+)
CBA/J MGP_CBAJ_G0022111
 protein coding gene Chr15:112195543-112203169 (+)
DBA/2J MGP_DBA2J_G0022242
 protein coding gene Chr15:99680121-99686788 (+)
FVB/NJ MGP_FVBNJ_G0022218
 protein coding gene Chr15:98742681-98749422 (+)
LP/J MGP_LPJ_G0022311
 protein coding gene Chr15:104659195-104667140 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022240
 protein coding gene Chr15:115757760-115766478 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022836
 protein coding gene Chr15:103460530-103467197 (+)
PWK/PhJ MGP_PWKPhJ_G0021408
 protein coding gene Chr15:99835671-99842253 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021240
 protein coding gene Chr15:103311992-103318435 (+)
WSB/EiJ MGP_WSBEiJ_G0021718
 protein coding gene Chr15:104090935-104097592 (+)



Homology
more
  • Human Ortholog
    MYG1, MYG1 exonuclease
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYG1, MYG1 exonuclease
  • Synonyms
    C12orf10, Gamm1, MST024, MSTP024, MYG
  • Links
    NCBI Gene ID: 60314
    neXtProt AC: NX_Q9HB07
    UniProt: Q9HB07

  • Chr Location
    12q13.13; chr12:53299695-53307177 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display no gross abnormalities but altered sex-dependent anxiety-like behaviors in different tests.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    41
  • cDNA Data
    78
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 60315 NCBI Gene Model | MGI Sequence Detail 6431 C57BL/6J ±  kb
transcript NM_021713 RefSeq | MGI Sequence Detail 1480 Not Specified  
polypeptide Q9JK81 UniProt | EBI | MGI Sequence Detail 380 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 79
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913314, MGI:1917221, MGI:1923320, MGI:2145985
References
more
  • Summaries
    All 56
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 26
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory