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Asb3 Gene Detail
Summary
  • Symbol
    Asb3
  • Name
    ankyrin repeat and SOCS box-containing 3
  • Synonyms
    2400011J03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929749
    NCBI Gene: 65257
  • Gene Overview
    MyGene.info: ASB3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:30954222-31102704 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 18.19 cM, cytoband A4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1269 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929749
protein coding gene Chr11:30885416-31102704 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018118
protein coding gene Chr11:29000834-29223757 (+)
A/J MGP_AJ_G0018091
protein coding gene Chr11:27919655-28124019 (+)
AKR/J MGP_AKRJ_G0018055
protein coding gene Chr11:28804850-29012963 (+)
BALB/cJ MGP_BALBcJ_G0018060
protein coding gene Chr11:28124316-28329993 (+)
C3H/HeJ MGP_C3HHeJ_G0017873
protein coding gene Chr11:28739761-28977209 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018511
protein coding gene Chr11:29958937-30191853 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0017435
protein coding gene Chr11:28828341-29032783 (+)
CBA/J MGP_CBAJ_G0017846
protein coding gene Chr11:31402440-31620973 (+)
DBA/2J MGP_DBA2J_G0017956
protein coding gene Chr11:27736891-27950898 (+)
FVB/NJ MGP_FVBNJ_G0017950
protein coding gene Chr11:27531294-27738884 (+)
LP/J MGP_LPJ_G0018028
protein coding gene Chr11:29244814-29456278 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017974
protein coding gene Chr11:32460172-32699694 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018552
protein coding gene Chr11:28903227-29133851 (+)
PWK/PhJ MGP_PWKPhJ_G0017217
protein coding gene Chr11:27836222-28052727 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017011
protein coding gene Chr11:28617039-28850255 (+)
WSB/EiJ MGP_WSBEiJ_G0017487
protein coding gene Chr11:28591713-28812300 (+)



Homology
more
  • Human Ortholog
    ASB3, ankyrin repeat and SOCS box containing 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ASB3, ankyrin repeat and SOCS box containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASB-3
  • Links
    NCBI Gene ID: 51130
    neXtProt AC: NX_Q9Y575
    UniProt: Q9Y575

  • Chr Location
    2p16.2; chr2:53669980-53787009 (-)  GRCh38.p7

  • Human Ortholog
    GPR75-ASB3, GPR75-ASB3 readthrough
    Orthology source: HomoloGene
  • Synonyms
    ASB3, ASB-3
  • Links
    NCBI Gene ID: 100302652
    neXtProt AC: NX_Q9Y575

  • Chr Location
    2p16.2; chr2:53670293-53860033 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 65257 NCBI Gene Model | MGI Sequence Detail 148483 C57BL/6J ±  kb
transcript NM_023906 RefSeq | MGI Sequence Detail 3225 C57BL/6  
polypeptide Q9WV72 UniProt | EBI | MGI Sequence Detail 525 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR037329 Ankyrin repeat and SOCS box protein 3, SOCS box domain
    IPR020683 Ankyrin repeat-containing domain
    IPR036770 Ankyrin repeat-containing domain superfamily
    IPR001496 SOCS box domain
    IPR036036 SOCS box-like domain superfamily
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 5
Other
Accession IDs
less
MGI:1926018
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory