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Rrs1 Gene Detail
Summary
  • Symbol
    Rrs1
  • Name
    ribosome biogenesis regulator 1
  • Synonyms
    5730466A07Rik, D1Ertd701e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929721
    NCBI Gene: 59014
  • Gene Overview
    MyGene.info: RRS1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:9545408-9547455 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    68 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929721
protein coding gene Chr1:9545408-9547455 (.)
129S1/SvImJ MGP_129S1SvImJ_G0015823
protein coding gene Chr1:6757105-6760099 (+)
A/J MGP_AJ_G0015805
protein coding gene Chr1:6848108-6850155 (+)
AKR/J MGP_AKRJ_G0015764
protein coding gene Chr1:6729336-6731858 (+)
BALB/cJ MGP_BALBcJ_G0015761
protein coding gene Chr1:6589465-6591512 (+)
C3H/HeJ MGP_C3HHeJ_G0015595
protein coding gene Chr1:6659883-6661925 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016215
protein coding gene Chr1:7111625-7113779 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013936
protein coding gene Chr1:5705339-5707414 (+)
CAST/EiJ MGP_CASTEiJ_G0015175
protein coding gene Chr1:6830612-6832704 (+)
CBA/J MGP_CBAJ_G0015568
protein coding gene Chr1:7267175-7269061 (+)
DBA/2J MGP_DBA2J_G0015668
protein coding gene Chr1:6483971-6485784 (+)
FVB/NJ MGP_FVBNJ_G0015672
protein coding gene Chr1:6395553-6398116 (+)
LP/J MGP_LPJ_G0029264
protein coding gene Chr5:24304885-24306658 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015691
protein coding gene Chr1:7899602-7903945 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016261
protein coding gene Chr1:6631575-6634728 (+)
PWK/PhJ MGP_PWKPhJ_G0014959
protein coding gene Chr1:6331637-6333099 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014739
protein coding gene Chr1:6803480-6804867 (+)
WSB/EiJ MGP_WSBEiJ_G0015239
protein coding gene Chr1:6657416-6659122 (+)



Homology
more
  • Human Ortholog
    RRS1, ribosome biogenesis regulator homolog
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RRS1, ribosome biogenesis regulator homolog
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23212
    neXtProt AC: NX_Q15050
    UniProt: Q15050

  • Chr Location
    8q13.1; chr8:66429028-66430733 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 59014 NCBI Gene Model | MGI Sequence Detail 2048 C57BL/6J ±  kb
transcript NM_021511 RefSeq | MGI Sequence Detail 2058 C57BL/6  
polypeptide Q9CYH6 UniProt | EBI | MGI Sequence Detail 365 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1289317, MGI:1915225, MGI:2138096
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory