About   Help   FAQ
Rrs1 Gene Detail
Summary
  • Symbol
    Rrs1
  • Name
    ribosome biogenesis regulator 1
  • Synonyms
    5730466A07Rik, D1Ertd701e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929721
    NCBI Gene: 59014
  • Gene Overview
    MyGene.info: RRS1
Location & Maps
more
  • Genetic Map
    Chromosome 1, 2.08 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RRS1, ribosome biogenesis regulator homolog
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RRS1, ribosome biogenesis regulator homolog
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 23212
    neXtProt AC: NX_Q15050

  • Chr Location
    8q13.1; chr8:66429028-66430733 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045230 VEGA Gene Model | MGI Sequence Detail 2048 C57BL/6J ±  kb
transcript OTTMUST00000118821 VEGA | MGI Sequence Detail 2048 Not Applicable  
polypeptide OTTMUSP00000066275 VEGA | MGI Sequence Detail 365 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014315 ribosome biogenesis regulatory protein
  • InterPro Domains
    IPR007023 Ribosomal biogenesis regulatory protein
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1289317, MGI:1915225, MGI:2138096
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/22/2016
MGI 6.04
The Jackson Laboratory