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Zfp191
Gene Detail
Symbol

Name
ID
Zfp191
zinc finger protein 191
MGI:1929704
Synonyms
3526401F17Rik, 5033419P20Rik, KOX17, ZF-12
Feature Type
protein coding gene
Genetic Map
Chromosome 18
12.55 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:24009702-24020810 bp, - strand
From VEGA annotation of GRCm38

  11109 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5068  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: ZNF24
Gene Tree: Zfp191

Human
homologs
ZNF24, zinc finger protein 24
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7572
neXtProt AC: NX_P17028

Human Synonyms: KOX17, RSG-A, Zfp191, ZNF191, ZSCAN3

Human Chr (Location): 18q12; chr18:35332214-35344462 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(9) Spontaneous(2) Targeted(4)
Incidental mutations (data from CvDC )
 
Mice homozygous null for one mutation have hypomyelination of the central nervous system, tremors, tonic seizures and premature death, whereas mice homozygous null for another mutation are embryonic lethal.
 
Interactions
Zfp191 interacts with 429 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process myelination, negative regulation of transcription, DNA-templated, ...
Component nucleoplasm, nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (397)    Tissues (306)    Images (64)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 384
Northern blot 12
RT-PCR 1
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000032638 (Evidence)
Ensembl Gene Model ENSMUSG00000051469 (Evidence)
Entrez Gene 59057 (Evidence)
DFCI TC1574637, TC1597674, TC1762676
DoTS DT.101189653, DT.530585, DT.91285829
NIA Mouse Gene Index U021081, U043887
Consensus CDS Project CCDS29098.1
International Mouse Phenotyping Consortium Status Zfp191
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032638 VEGA Gene Model | MGI Sequence Detail 11109 C57BL/6J ±  kb
transcript OTTMUST00000081194 VEGA | MGI Sequence Detail 5732 Not Applicable 
polypeptide OTTMUSP00000043388 VEGA | MGI Sequence Detail 368 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(115 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008916 Retrovirus capsid, C-terminal
InterPro IPR003309 SCAN domain
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017775 zinc finger protein 24
References
(Earliest) J:66304 Prost JF, et al., Isolation, cloning, and expression of a new murine zinc finger encoding gene. Biochim Biophys Acta. 1999 Oct 28;1447(2-3):278-83
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)
Other
accession IDs
MGI:1918016, MGI:1923242, MGI:2147238, MGI:2147248, MGI:2147290

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory