About   Help   FAQ
Slc37a2 Gene Detail
Summary
  • Symbol
    Slc37a2
  • Name
    solute carrier family 37 (glycerol-3-phosphate transporter), member 2
  • Synonyms
    ci2, cI-2, G3PP, Slc37a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929693
    NCBI Gene: 56857
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:37140445-37166709 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 20.74 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    876 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929693
 protein coding gene Chr9:37138881-37167034 (-)
129S1/SvImJ ENSMUSG00200037674
 protein coding gene Chr9:34126173-34154325 (-)
A/J ENSMUSG00195047904
 protein coding gene Chr9:33912784-33940934 (-)
AKR/J ENSMUSG00220042829
 protein coding gene Chr9:33989846-34017568 (-)
BALB/cJ ENSMUSG00180043190
 protein coding gene Chr9:34041106-34069256 (-)
C3H/HeJ ENSMUSG00175047398
 protein coding gene Chr9:34042136-34070286 (-)
C57BL/6NJ ENSMUSG00215032358
 protein coding gene Chr9:34044728-34072882 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031978
 protein coding gene Chr9:33385739-33412113 (-)
CAST/EiJ ENSTCUG00005041778
 protein coding gene Chr9:34005627-34033540 (-)
CBA/J ENSMUSG00210041690
 protein coding gene Chr9:34039121-34067270 (-)
DBA/2J ENSMUSG00185031324
 protein coding gene Chr9:34139260-34166977 (-)
FVB/NJ ENSMUSG00205034903
 protein coding gene Chr9:34404419-34432573 (-)
JF1/MsJ ENSUMUG00000031755
 protein coding gene Chr9:34243128-34270110 (-)
LP/J ENSMUSG00230028992
 protein coding gene Chr9:34500954-34527929 (-)
NOD/ShiLtJ ENSMUSG00190029488
 protein coding gene Chr9:34170364-34198059 (-)
NZO/HlLtJ ENSMUSG00225020315
 protein coding gene Chr9:34469372-34496347 (-)
PWK/PhJ ENSLUMG00010038388
 protein coding gene Chr9:34183684-34211487 (-)
SPRET/EiJ ENSMSPG00010027740
 protein coding gene Chr9:34745748-34772506 (-)
WSB/EiJ ENSIUOG00005039760
 protein coding gene Chr9:33664109-33691826 (-)



Homology
more
  • Human Ortholog
    SLC37A2, solute carrier family 37 member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC37A2, solute carrier family 37 member 2
  • Synonyms
    pp11662, SPX2
  • Links
    NCBI Gene ID: 219855
    UniProt: Q8TED4

  • Chr Location
    11q24.2; chr11:125063302-125090516 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased pro-inflammatory cytokine production and accelerated glycolysis and mitochondrial oxidation in macrophages.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    636
  • Tissues
    39
  • cDNA Data
    29
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56857 NCBI Gene Model | MGI Sequence Detail 26265 C57BL/6J ±  kb
    transcript NM_001145960 RefSeq | MGI Sequence Detail 4111 C57BL/6  
    polypeptide Q9WU81 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      Genomic 2
      cDNA 29
      Primer pair 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:66225 Bartoloni L, et al., Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency. Genomics. 2000 Dec 1;70(2):190-200
    • Latest
      J:376309 Viscomi MP, et al., Embryonic and placental factors are linked with the development of autism-like behaviors in the BTBR mouse model. Neuroscience. 2025 Dec 5;593:18-28
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory