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Mllt11 Gene Detail
Summary
  • Symbol
    Mllt11
  • Name
    myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
  • Synonyms
    Af1q
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929671
    NCBI Gene: 56772
  • Gene Overview
    MyGene.info: MLLT11
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95219135-95232171 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929671
protein coding gene Chr3:95218544-95232197 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027575
protein coding gene Chr3:95925482-95939709 (-)
A/J MGP_AJ_G0027534
protein coding gene Chr3:92961024-92974211 (-)
AKR/J MGP_AKRJ_G0027501
protein coding gene Chr3:95106675-95120322 (-)
BALB/cJ MGP_BALBcJ_G0027546
protein coding gene Chr3:92737265-92752198 (-)
C3H/HeJ MGP_C3HHeJ_G0027279
protein coding gene Chr3:95393222-95406555 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027994
protein coding gene Chr3:99492999-99506046 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025334
protein coding gene Chr3:89322689-89335721 (-)
CAST/EiJ MGP_CASTEiJ_G0026729
protein coding gene Chr3:94671829-94687778 (-)
CBA/J MGP_CBAJ_G0027256
protein coding gene Chr3:103098916-103111939 (-)
DBA/2J MGP_DBA2J_G0027395
protein coding gene Chr3:92252718-92266481 (-)
FVB/NJ MGP_FVBNJ_G0027366
protein coding gene Chr3:90325421-90341692 (-)
LP/J MGP_LPJ_G0027504
protein coding gene Chr3:97230382-97245233 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027393
protein coding gene Chr3:109216198-109230694 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028048
protein coding gene Chr3:94763467-94777513 (-)
PWK/PhJ MGP_PWKPhJ_G0026457
protein coding gene Chr3:92130751-92144477 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026278
protein coding gene Chr3:93057993-93070940 (-)
WSB/EiJ MGP_WSBEiJ_G0026811
protein coding gene Chr3:95147397-95161373 (-)



Homology
more
  • Human Ortholog
    MLLT11, MLLT11 transcription factor 7 cofactor
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MLLT11, MLLT11 transcription factor 7 cofactor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AF1Q
  • Links
    NCBI Gene ID: 10962
    neXtProt AC: NX_Q13015
    UniProt: Q13015

  • Chr Location
    1q21.3; chr1:151059675-151068497 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053192 Ensembl Gene Model | MGI Sequence Detail 13037 C57BL/6J ±  kb
transcript ENSMUST00000198948 Ensembl | MGI Sequence Detail 793 Not Applicable  
polypeptide ENSMUSP00000142604 Ensembl | MGI Sequence Detail 90 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139804
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:214315 Yamada M, et al., MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory