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Cript Gene Detail
Summary
  • Symbol
    Cript
  • Name
    cysteine-rich PDZ-binding protein
  • Synonyms
    1200020A08Rik, CRIPT
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929655
    NCBI Gene: 56724
  • Gene Overview
    MyGene.info: CRIPT
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:87025561-87035808 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 56.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    125 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929655
protein coding gene Chr17:87025550-87035810 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024098
protein coding gene Chr17:90376558-90391097 (+)
A/J MGP_AJ_G0024057
protein coding gene Chr17:87467762-87479607 (+)
AKR/J MGP_AKRJ_G0024026
protein coding gene Chr17:88941312-88953157 (+)
BALB/cJ MGP_BALBcJ_G0024058
protein coding gene Chr17:87316421-87330131 (+)
C3H/HeJ MGP_C3HHeJ_G0023823
protein coding gene Chr17:89803477-89817192 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024503
protein coding gene Chr17:93505322-93519292 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021942
protein coding gene Chr17:82627995-82638383 (+)
CAST/EiJ MGP_CASTEiJ_G0023302
protein coding gene Chr17:90634830-90643590 (+)
CBA/J MGP_CBAJ_G0023797
protein coding gene Chr17:97434029-97446652 (+)
DBA/2J MGP_DBA2J_G0023925
protein coding gene Chr17:85918012-85927647 (+)
FVB/NJ MGP_FVBNJ_G0023891
protein coding gene Chr17:85422572-85433246 (+)
LP/J MGP_LPJ_G0024009
protein coding gene Chr17:91163752-91174024 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023919
protein coding gene Chr17:97338721-97349990 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024548
protein coding gene Chr17:89459485-89469929 (+)
PWK/PhJ MGP_PWKPhJ_G0023047
protein coding gene Chr17:85551699-85561341 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022858
protein coding gene Chr17:86210369-86227698 (+)
WSB/EiJ MGP_WSBEiJ_G0023368
protein coding gene Chr17:90301507-90310419 (+)



Homology
more
  • Human Ortholog
    CRIPT, CXXC repeat containing interactor of PDZ3 domain
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRIPT, CXXC repeat containing interactor of PDZ3 domain
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC139, SSMDF
  • Links
    NCBI Gene ID: 9419
    neXtProt AC: NX_Q9P021
    UniProt: Q9P021

  • Chr Location
    2p21; chr2:46617172-46630176 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8572
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CRIPT
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a transposon induced allele exhibit embryonic lethality at E8.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56724 NCBI Gene Model | MGI Sequence Detail 10248 C57BL/6J ±  kb
transcript NM_019936 RefSeq | MGI Sequence Detail 1171 C57BL/6  
polypeptide O70333 UniProt | EBI | MGI Sequence Detail 101 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR019367 PDZ-binding protein, CRIPT
Molecular
Reagents
less
  • All nucleic 104
    cDNA 104

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915245, MGI:2144029
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:255313 Leduc MS, et al., CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities. Am J Med Genet A. 2016 Aug;170(8):2206-11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory