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Pmepa1 Gene Detail
Summary
  • Symbol
    Pmepa1
  • Name
    prostate transmembrane protein, androgen induced 1
  • Synonyms
    2210418I02Rik, N4wbp4, PMEPA1, STAG1, Tmepai
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929600
    NCBI Gene: 65112
  • Gene Overview
    MyGene.info: PMEPA1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:173224458-173276533 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 95.85 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    598 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929600
protein coding gene Chr2:173224458-173276731 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026956
protein coding gene Chr2:179484476-179545934 (-)
A/J MGP_AJ_G0026923
protein coding gene Chr2:171937207-171990298 (-)
AKR/J MGP_AKRJ_G0026894
protein coding gene Chr2:177122258-177174461 (-)
BALB/cJ MGP_BALBcJ_G0026932
protein coding gene Chr2:172338960-172391271 (-)
C3H/HeJ MGP_C3HHeJ_G0026674
protein coding gene Chr2:177512314-177566194 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027379
protein coding gene Chr2:184649844-184705370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024749
protein coding gene Chr2:165173780-165225226 (-)
CAST/EiJ MGP_CASTEiJ_G0026132
protein coding gene Chr2:178206307-178260715 (-)
CBA/J MGP_CBAJ_G0026651
protein coding gene Chr2:191553313-191610020 (-)
DBA/2J MGP_DBA2J_G0026789
protein coding gene Chr2:171030225-171082155 (-)
FVB/NJ MGP_FVBNJ_G0026755
protein coding gene Chr2:169650903-169710175 (-)
LP/J MGP_LPJ_G0026890
protein coding gene Chr2:179416780-179473601 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026774
protein coding gene Chr2:194485225-194542460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027436
protein coding gene Chr2:177146282-177202704 (-)
PWK/PhJ MGP_PWKPhJ_G0025869
protein coding gene Chr2:170831355-170885048 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025669
protein coding gene Chr2:176146031-176201954 (-)
WSB/EiJ MGP_WSBEiJ_G0026205
protein coding gene Chr2:178090896-178150136 (-)



Homology
more
  • Human Ortholog
    PMEPA1, prostate transmembrane protein, androgen induced 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PMEPA1, prostate transmembrane protein, androgen induced 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    STAG1, TMEPAI
  • Links
    NCBI Gene ID: 56937
    neXtProt AC: NX_Q969W9
    UniProt: Q969W9

  • Chr Location
    20q13.31; chr20:57648392-57711536 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038400 Ensembl Gene Model | MGI Sequence Detail 52076 C57BL/6J ±  kb
transcript ENSMUST00000036248 Ensembl | MGI Sequence Detail 4538 Not Applicable  
polypeptide ENSMUSP00000039950 Ensembl | MGI Sequence Detail 274 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 126
    cDNA 125
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917408, MGI:2139348
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:283975 Xu X, et al., Prostate transmembrane protein androgen induced 1 is induced by activation of osteoclasts and regulates bone resorption. FASEB J. 2019 Mar;33(3):4365-4375

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/20/2020
MGI 6.16
The Jackson Laboratory