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Dap3
Gene Detail
Symbol

Name
ID
Dap3
death associated protein 3
MGI:1929538
Synonyms
4921514D13Rik, DAP-3
Feature Type
protein coding gene
Genetic Map
Chromosome 3
39.01 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:88920803-88951181 bp, - strand
From VEGA annotation of GRCm38

  30379 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3404  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DAP3
Protein SuperFamily: death-associated protein 3
Gene Tree: Dap3

Human
homologs
DAP3, death associated protein 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7818
neXtProt AC: NX_P51398

Human Synonyms: bMRP-10, DAP-3, MRPS29, MRP-S29

Human Chr (Location): 1q22; chr1:155689089-155739010 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(26)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display embryonic lethality with defects in mitochondria morphology.
 
Interactions
Dap3 interacts with 247 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process apoptotic mitochondrial changes, apoptotic process
Component mitochondrial matrix, mitochondrial ribosome, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (55)    Tissues (55)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 43
Northern blot 12
cDNA source data(157)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase dap3 ; ZFIN dap3    NEW 
Molecular
reagents
All nucleic(158) cDNA(158)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000031317 (Evidence)
Ensembl Gene Model ENSMUSG00000068921 (Evidence)
Entrez Gene 65111 (Evidence)
UniGene 29028
DFCI TC1574366, TC1590120
DoTS DT.495162, DT.103574626, DT.101736514
NIA Mouse Gene Index U024266
Consensus CDS Project CCDS17486.2, CCDS50955.1
International Mouse Phenotyping Consortium Status Dap3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031317 VEGA Gene Model | MGI Sequence Detail 30379 C57BL/6J ±  kb
transcript OTTMUST00000077574 VEGA | MGI Sequence Detail 4760 Not Applicable 
polypeptide OTTMUSP00000041067 VEGA | MGI Sequence Detail 396 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(20) UniProt(9)
Polymorphisms
SNPs within 2kb(113 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR019368 Ribosomal protein S23/S29, mitochondrial
InterPro IPR008092 Ribosomal protein S29, mitochondrial
Protein Ontology PR:000006275 28S ribosomal protein S29, mitochondrial
References
(Earliest) J:65635 Berger T, et al., The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins. J Cell Sci. 2000 Oct;113(Pt 20):3603-12
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:1913973

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory