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Dap3
Gene Detail
Symbol

Name
ID
Dap3
death associated protein 3
MGI:1929538
Synonyms
4921514D13Rik, DAP-3
Feature Type
protein coding gene
Genetic Map
Chromosome 3
39.01 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:88920803-88951181 bp, - strand
From VEGA annotation of GRCm38

  30379 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3404  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: death-associated protein 3
Gene Tree: Dap3

Human
homologs
Human Homolog DAP3, death associated protein 3
NCBI Gene ID 7818
neXtProt AC  NX_P51398
Human Synonyms  bMRP-10, DAP-3, MRPS29, MRP-S29
Human Chr (Location)  1q22; chr1:155689062-155739010 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(26)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display embryonic lethality with defects in mitochondria morphology.
 
Interactions
Dap3 interacts with 248 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process apoptotic mitochondrial changes, apoptotic process
Component mitochondrial matrix, mitochondrial ribosome, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (55)    Tissues (55)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 43
Northern blot 12
cDNA source data(157)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(158) cDNA(158)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031317 (Evidence)
Ensembl Gene ModelENSMUSG00000068921 (Evidence)
Entrez Gene65111 (Evidence)
UniGene29028
DFCITC1574366, TC1590120
DoTSDT.101736514, DT.103574626, DT.495162
NIA Mouse Gene IndexU024266
Consensus CDS ProjectCCDS17486.2, CCDS50955.1
International Mouse Knockout Project StatusDap3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031317 VEGA Gene Model | MGI Sequence Detail 30379 C57BL/6J ±  kb
transcript OTTMUST00000077574 VEGA | MGI Sequence Detail 4760 Not Applicable 
polypeptide OTTMUSP00000041067 VEGA | MGI Sequence Detail 396 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(22) UniProt(17)
Polymorphisms
SNPs within 2kb(113 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR019368 Ribosomal protein S23/S29, mitochondrial
InterPro IPR008092 Ribosomal protein S29, mitochondrial
Protein Ontology PR:000006275 28S ribosomal protein S29, mitochondrial
References
(Earliest) J:65635 Berger T, et al., The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins. J Cell Sci. 2000 Oct;113(Pt 20):3603-12
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGI:1913973

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory