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Eef1b2 Gene Detail
Summary
  • Symbol
    Eef1b2
  • Name
    eukaryotic translation elongation factor 1 beta 2
  • Synonyms
    2810017J07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929520
    NCBI Gene: 55949
  • Gene Overview
    MyGene.info: EEF1B2
Location & Maps
more
  • Sequence Map
    Chr1:63176825-63180486 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3662 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 32.31 cM, cytoband C2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EEF1B2, eukaryotic translation elongation factor 1 beta 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EEF1B2, eukaryotic translation elongation factor 1 beta 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EEF1B, EEF1B1, EF1B
  • Links
    NCBI Gene ID: 1933
    neXtProt AC: NX_P24534

  • Chr Location
    2q33.3; chr2:206159594-206162929 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    58
  • Chemically induced (other)
    1
  • Gene trapped
    53
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Eef1b2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002614 VEGA Gene Model | MGI Sequence Detail 3662 C57BL/6J ±  kb
transcript OTTMUST00000005070 VEGA | MGI Sequence Detail 1939 Not Applicable  
polypeptide OTTMUSP00000002423 VEGA | MGI Sequence Detail 225 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    26 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000006905 elongation factor 1-beta
  • InterPro Domains
    IPR018940 Elongation factor 1 beta central acidic region, eukaryote
    IPR010987 Glutathione S-transferase, C-terminal-like
    IPR001326 Translation elongation factor EF1B, beta/delta chains, conserved site
    IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain
    IPR014717 Translation elongation factor EF1B/ribosomal protein S6
Molecular
Reagents
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  • All nucleic 531
    Genomic 1
    cDNA 529
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:1919870
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:65628 Liu Q, et al., Molecular cloning and tissue expression analysis of the beta subunit of elongation factor 1 in the mouse. Biochem Genet. 2000 Apr;38(3-4):111-7
  • Latest
    J:207604 Duffie R, et al., The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals. Genes Dev. 2014 Mar 1;28(5):463-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory