Zic5
Gene Detail

Symbol

Name
ID

Zic5
zinc finger protein of the cerebellum 5
MGI:1929518

Synonyms

1700049L20Rik, odd-paired related, Opr

Feature Type

protein coding gene

Genetic Map

Chromosome 14
65.96 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:122456795-122465677 bp, - strand From VEGA annotation of GRCm38   8883 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:11301  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog

Gene Tree: Zic5

Human
homologs

Human Homolog		ZIC5, Zic family member 5
NCBI Gene ID		85416
neXtProt AC		NX_Q96T25
Human Chr (Location)		13q32.3; chr13:99963021-99971924 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 

Homozygous null mice display postnatal lethality and reduced life spans with exencephaly, abnormal cerebral cortex and diencephalon morphology, abnormal gait and posture, and impaired growth.

 

Interactions

Zic5 interacts with 390 markers (Mir1a-1, Mir1a-2, Mir1b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (12 annotations)

Process	cell differentiation, forebrain development, ...
Component	nucleus
Function	DNA binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (12 records)

Data Summary: Results (143)    Tissues (109)    Images (31)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	118
RT-PCR	25

cDNA source data(3)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(7) cDNA(3) Primer pair(4)
Microarray probesets(4)

Other database
links

VEGA Gene Model	OTTMUSG00000020976 (Evidence)
Ensembl Gene Model	ENSMUSG00000041703 (Evidence)
Entrez Gene	65100 (Evidence)
NIA Mouse Gene Index	U045833, U035955
Consensus CDS Project	CCDS27348.1
International Mouse Knockout Project Status	Zic5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020976	VEGA Gene Model | MGI Sequence Detail	8883	C57BL/6J
transcript	OTTMUST00000049605	VEGA | MGI Sequence Detail	4767	Not Applicable
polypeptide	OTTMUSP00000023013	VEGA | MGI Sequence Detail	622	Not Applicable

All sequences(23) RefSeq(4) UniProt(3)

Polymorphisms

SNPs within 2kb(13 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology	PR:000017669	zinc finger protein ZIC 5

References

(Earliest) J:65637 Furushima K, et al., A new murine zinc finger gene, Opr. Mech Dev. 2000 Nov;98(1-2):161-4
(Latest) J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
All references(35)

Other
accession IDs

MGI:1920601