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Zic5
Gene Detail
Symbol

Name
ID
Zic5
zinc finger protein of the cerebellum 5
MGI:1929518
Synonyms
1700049L20Rik, odd-paired related, Opr
Feature Type
protein coding gene
Genetic Map
Chromosome 14
65.96 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:122456795-122465677 bp, - strand
From VEGA annotation of GRCm38

  8883 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11301  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog

Gene Tree: Zic5

Human
homologs
Human Homolog ZIC5, Zic family member 5
NCBI Gene ID 85416
neXtProt AC  NX_Q96T25
Human Chr (Location)  13q32.3; chr13:99963021-99971924 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display postnatal lethality and reduced life spans with exencephaly, abnormal cerebral cortex and diencephalon morphology, abnormal gait and posture, and impaired growth.
 
Interactions
Zic5 interacts with 390 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell differentiation, forebrain development, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (143)    Tissues (109)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
RT-PCR 25
cDNA source data(3)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(3) Primer pair(4)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000020976 (Evidence)
Ensembl Gene ModelENSMUSG00000041703 (Evidence)
Entrez Gene65100 (Evidence)
NIA Mouse Gene IndexU045833, U035955
Consensus CDS ProjectCCDS27348.1
International Mouse Knockout Project StatusZic5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020976 VEGA Gene Model | MGI Sequence Detail 8883 C57BL/6J ±  kb
transcript OTTMUST00000049605 VEGA | MGI Sequence Detail 4767 Not Applicable 
polypeptide OTTMUSP00000023013 VEGA | MGI Sequence Detail 622 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017669 zinc finger protein ZIC 5
References
(Earliest) J:65637 Furushima K, et al., A new murine zinc finger gene, Opr. Mech Dev. 2000 Nov;98(1-2):161-4
(Latest) J:198578 Chervenak AP, et al., Spatiotemporal expression of zic genes during vertebrate inner ear development. Dev Dyn. 2013 Jul;242(7):897-908
All references(34)
Other
accession IDs
MGI:1920601

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory