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Ndufa1
Gene Detail
 Symbol
Name
ID
Ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
MGI:1929511
Synonyms 1810049F12Rik, MWFE
Feature Type protein coding gene
Genetic Map
Chromosome X
21.61 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:37187588-37191163 bp, - strand
From VEGA annotation of GRCm38

  3576 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3337  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 3 rhesus macaque; 1 cattle; 2 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
Gene Tree: Ndufa1

Human
homologs
Human Homolog NDUFA1, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NCBI Gene ID 4694
neXtProt AC  NX_O15239
Human Synonyms  CI-MWFE, MWFE, ZNF183
Human Chr (Location)  Xq24; chrX:119871771-119876666 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NDUFA1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Interactions
Ndufa1 interacts with 23 markers (Mir33, Mir320, Mir491, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process oxidation-reduction process, transport
Component integral component of membrane, membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (117)    Tissues (98)    Images (22)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 117
cDNA source data(149)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(150) cDNA(150)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000017127 (Evidence)
Ensembl Gene ModelENSMUSG00000016427 (Evidence)
Entrez Gene54405 (Evidence)
UniGene34869
DFCITC1572706, TC1668028
NIA Mouse Gene IndexU039320
Consensus CDS ProjectCCDS40928.1
International Mouse Knockout Project StatusNdufa1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017127 VEGA Gene Model | MGI Sequence Detail 3576 C57BL/6J ±  kb
transcript OTTMUST00000041470 VEGA | MGI Sequence Detail 419 Not Applicable 
polypeptide OTTMUSP00000018617 VEGA | MGI Sequence Detail 70 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(8 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017384 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
Protein Ontology PR:000011067 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
References (Earliest) J:66313 Frattini A, et al., Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25. Gene. 1997 Jun 19;192(2):291-8
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(36)
Other
accession IDs
MGI:1923962

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory