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Arl6ip6 Gene Detail
Summary
  • Symbol
    Arl6ip6
  • Name
    ADP-ribosylation factor-like 6 interacting protein 6
  • Synonyms
    2310057C01Rik, 2610529A11Rik, Aip-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929507
    NCBI Gene: 65103
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:53192084-53219221 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 30.69 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929507
protein coding gene Chr2:53191726-53219221 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025739
protein coding gene Chr2:52581363-52614762 (+)
A/J MGP_AJ_G0025715
protein coding gene Chr2:50538176-50572387 (+)
AKR/J MGP_AKRJ_G0025685
protein coding gene Chr2:51984704-52014075 (+)
BALB/cJ MGP_BALBcJ_G0025710
protein coding gene Chr2:50643503-50672780 (+)
C3H/HeJ MGP_C3HHeJ_G0025471
protein coding gene Chr2:52008348-52039867 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026156
protein coding gene Chr2:54106615-54144141 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023562
protein coding gene Chr2:48507141-48536256 (+)
CAST/EiJ MGP_CASTEiJ_G0024936
protein coding gene Chr2:52126302-52158488 (+)
CBA/J MGP_CBAJ_G0025451
protein coding gene Chr2:56167452-56195904 (+)
DBA/2J MGP_DBA2J_G0025582
protein coding gene Chr2:50185614-50213920 (+)
FVB/NJ MGP_FVBNJ_G0025544
protein coding gene Chr2:49871260-49898689 (+)
LP/J MGP_LPJ_G0025670
protein coding gene Chr2:52484879-52517154 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025575
protein coding gene Chr2:57167767-57196884 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026214
protein coding gene Chr2:51917943-51954620 (+)
PWK/PhJ MGP_PWKPhJ_G0024677
protein coding gene Chr2:50074269-50103218 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024483
protein coding gene Chr2:52148293-52179047 (+)
WSB/EiJ MGP_WSBEiJ_G0025003
protein coding gene Chr2:52205388-52234839 (+)



Homology
more
  • Human Ortholog
    ARL6IP6, ADP ribosylation factor like GTPase 6 interacting protein 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ARL6IP6, ADP ribosylation factor like GTPase 6 interacting protein 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AIP6, AIP-6, PFAAP1
  • Links
    NCBI Gene ID: 151188
    neXtProt AC: NX_Q8N6S5
    UniProt: Q8N6S5

  • Chr Location
    2q23.3; chr2:152717893-152761253 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 65103 NCBI Gene Model | MGI Sequence Detail 27138 C57BL/6J ±  kb
transcript NM_022989 RefSeq | MGI Sequence Detail 2553 C57BL/6  
polypeptide Q8BH07 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000004294 ADP-ribosylation factor-like protein 6-interacting protein 6
  • InterPro Domains
    IPR029383 ADP-ribosylation factor-like protein 6-interacting protein 6
Molecular
Reagents
less
  • All nucleic 74
    cDNA 74

    Microarray probesets 5
Other
Accession IDs
less
MGI:1914875, MGI:1922841
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:62458 Ingley E, et al., A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit. FEBS Lett. 1999 Oct 1;459(1):69-74
  • Latest
    J:276404 Cheng LC, et al., Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells. Nucleus. 2019 Dec;10(1):126-143

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory