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Arl6ip4 Gene Detail
Summary
  • Symbol
    Arl6ip4
  • Name
    ADP-ribosylation factor-like 6 interacting protein 4
  • Synonyms
    Aip-4, Srp25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929500
    NCBI Gene: 65105
  • Gene Overview
    MyGene.info: ARL6IP4
Location & Maps
more
  • Sequence Map
    Chr5:124116089-124118196 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2108 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 63.39 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ARL6IP4, ADP ribosylation factor like GTPase 6 interacting protein 4
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ARL6IP4, ADP ribosylation factor like GTPase 6 interacting protein 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SFRS20, SR-25, SRp25, SRrp37
  • Links
    NCBI Gene ID: 51329
    neXtProt AC: NX_Q66PJ3

  • Chr Location
    12q24.31; chr12:122980060-122982913 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Arl6ip4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028866 VEGA Gene Model | MGI Sequence Detail 2108 C57BL/6J ±  kb
transcript OTTMUST00000071488 VEGA | MGI Sequence Detail 1192 Not Applicable  
polypeptide OTTMUSP00000036635 VEGA | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    21 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004292 ADP-ribosylation factor-like protein 6-interacting protein 4
  • InterPro Domains
    IPR019532 Nuclear RNA-splicing-associated protein, SR-25
Molecular
Reagents
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  • All nucleic 80
    cDNA 78
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2140732, MGI:2140735
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:62458 Ingley E, et al., A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit. FEBS Lett. 1999 Oct 1;459(1):69-74
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory