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Lrp10 Gene Detail
Summary
  • Symbol
    Lrp10
  • Name
    low-density lipoprotein receptor-related protein 10
  • Synonyms
    Lrp9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929480
    NCBI Gene: 65107
  • Gene Overview
    MyGene.info: LRP10
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:54464147-54470292 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    87 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929480
protein coding gene Chr14:54464137-54471497 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021310
protein coding gene Chr14:48415586-48424193 (+)
A/J MGP_AJ_G0021269
protein coding gene Chr14:47474035-47481395 (+)
AKR/J MGP_AKRJ_G0021245
protein coding gene Chr14:49188620-49195960 (+)
BALB/cJ MGP_BALBcJ_G0021273
protein coding gene Chr14:47444490-47451984 (+)
C3H/HeJ MGP_C3HHeJ_G0021053
protein coding gene Chr14:48878557-48888500 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021712
protein coding gene Chr14:50870602-50877935 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019256
protein coding gene Chr14:45894324-45901559 (+)
CAST/EiJ MGP_CASTEiJ_G0020572
protein coding gene Chr14:45120294-45127620 (+)
CBA/J MGP_CBAJ_G0021020
protein coding gene Chr14:52376509-52387155 (+)
DBA/2J MGP_DBA2J_G0021141
protein coding gene Chr14:47217902-47225240 (+)
FVB/NJ MGP_FVBNJ_G0021123
protein coding gene Chr14:46672642-46680237 (+)
LP/J MGP_LPJ_G0021215
protein coding gene Chr14:49420423-49428155 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021147
protein coding gene Chr14:51814225-51821565 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021738
protein coding gene Chr14:48373186-48384059 (+)
PWK/PhJ MGP_PWKPhJ_G0020318
protein coding gene Chr14:43746800-43754880 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020146
protein coding gene Chr14:44361501-44368848 (+)
WSB/EiJ MGP_WSBEiJ_G0020625
protein coding gene Chr14:48670559-48678965 (+)



Homology
more
  • Human Ortholog
    LRP10, LDL receptor related protein 10
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LRP10, LDL receptor related protein 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRP-10, LRP9, MST087, MSTP087
  • Links
    NCBI Gene ID: 26020
    neXtProt AC: NX_Q7Z4F1
    UniProt: Q7Z4F1

  • Chr Location
    14q11.2; chr14:22871613-22881580 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8535
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRP10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 65107 NCBI Gene Model | MGI Sequence Detail 6146 C57BL/6J ±  kb
transcript NM_022993 RefSeq | MGI Sequence Detail 3013 C57BL/6  
polypeptide NP_075369 RefSeq | MGI Sequence Detail 713 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 141
    cDNA 140
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 7
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:36742 Pons S, et al., The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase. Mol Cell Biol. 1995 Aug;15(8):4453-65
  • Latest
    J:244839 Kimura-Yoshida C, et al., Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. EBioMedicine. 2015 Jun;2(6):513-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory