About   Help   FAQ
Lamtor3 Gene Detail
Summary
  • Symbol
    Lamtor3
  • Name
    late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
  • Synonyms
    Map2k1ip1, Mapksp1, MEK binding partner 1, Mp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929467
    NCBI Gene: 56692
  • Gene Overview
    MyGene.info: LAMTOR3
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr3:137918506-137928900 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10395 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 63.97 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LAMTOR3, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LAMTOR3, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
  • Links
    NCBI Gene ID: 8649
    neXtProt AC: NX_Q9UHA4
    UniProt: Q9UHA4

  • Chr Location
    4q23; chr4:99878338-99894546 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052741 VEGA Gene Model | MGI Sequence Detail 10395 C57BL/6J ±  kb
transcript OTTMUST00000132037 VEGA | MGI Sequence Detail 733 Not Applicable  
polypeptide OTTMUSP00000070468 VEGA | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    167 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 80
    cDNA 80

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140008
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:216883 Schiefermeier N, et al., The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration. J Cell Biol. 2014 May 26;205(4):525-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/31/2018
MGI 6.12
The Jackson Laboratory