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Cib2
Gene Detail
 Symbol
Name
ID
Cib2
calcium and integrin binding family member 2
MGI:1929293
Synonyms 2810434I23Rik, calcium binding protein Kip2
Feature Type protein coding gene
Genetic Map
Chromosome 9
29.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:54544794-54560218 bp, - strand
From VEGA annotation of GRCm38

  15425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cib2

Human
homologs
Human Homolog CIB2, calcium and integrin binding family member 2
NCBI Gene ID 10518
neXtProt AC  NX_O75838
Human Synonyms  DFNB48, KIP2, USH1J
Human Chr (Location)  15q24; chr15:78104606-78131535 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human CIB2
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cib2 interacts with 91 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process calcium ion homeostasis, integrin-mediated signaling pathway, ...
Component blood microparticle, membrane, ...
Function calcium ion binding, integrin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (78)    Tissues (24)    Images (32)
Theiler Stages: 21, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 8
RNA in situ 28
Northern blot 24
Western blot 2
RT-PCR 16
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000030276 (Evidence)
Ensembl Gene ModelENSMUSG00000037493 (Evidence)
Entrez Gene56506 (Evidence)
NIA Mouse Gene IndexU030884
Consensus CDS ProjectCCDS40642.1
International Mouse Knockout Project StatusCib2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030276 VEGA Gene Model | MGI Sequence Detail 15425 C57BL/6J ±  kb
transcript OTTMUST00000074950 VEGA | MGI Sequence Detail 1433 Not Applicable 
polypeptide OTTMUSP00000039202 VEGA | MGI Sequence Detail 187 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000032050 calcium and integrin-binding family member 2
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:196222 Riazuddin S, et al., Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. Nat Genet. 2012 Nov;44(11):1265-71
All references(34)
Other
accession IDs
MGI:1915156, MGI:2143056

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory