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Cib2
Gene Detail
Symbol

Name
ID
Cib2
calcium and integrin binding family member 2
MGI:1929293
Synonyms
2810434I23Rik, calcium binding protein Kip2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
29.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:54544794-54560218 bp, - strand
From VEGA annotation of GRCm38

  15425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CIB2
Gene Tree: Cib2

Human
homologs
CIB2, calcium and integrin binding family member 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10518
neXtProt AC: NX_O75838

Human Synonyms: DFNB48, KIP2, USH1J

Human Chr (Location): 15q24; chr15:78104606-78131721 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human CIB2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cib2 interacts with 90 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process calcium ion homeostasis, photoreceptor cell maintenance
Component blood microparticle, membrane, ...
Function calcium ion binding, integrin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (78)    Tissues (25)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 8
RNA in situ 28
Northern blot 24
Western blot 2
RT-PCR 16
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cib2 ; ZFIN cib2    NEW 
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000030276 (Evidence)
Ensembl Gene Model ENSMUSG00000037493 (Evidence)
Entrez Gene 56506 (Evidence)
NIA Mouse Gene Index U030884
Consensus CDS Project CCDS40642.1
International Mouse Phenotyping Consortium Status Cib2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030276 VEGA Gene Model | MGI Sequence Detail 15425 C57BL/6J ±  kb
transcript OTTMUST00000074950 VEGA | MGI Sequence Detail 1433 Not Applicable 
polypeptide OTTMUSP00000039202 VEGA | MGI Sequence Detail 187 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000032050 calcium and integrin-binding family member 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:218725 Cosgrove D, et al., Usher protein functions in hair cells and photoreceptors. Int J Biochem Cell Biol. 2014 Jan;46:80-9
All references(34)
Other
accession IDs
MGI:1915156, MGI:2143056

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory