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Orc6 Gene Detail
Summary
  • Symbol
    Orc6
  • Name
    origin recognition complex, subunit 6
  • Synonyms
    6720420I10Rik, Orc6l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929285
    NCBI Gene: 56452
Location & Maps
more
  • Sequence Map
    Chr8:85299632-85308278 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8647 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    ORC6, origin recognition complex subunit 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ORC6, origin recognition complex subunit 6
    Orthology source: HomoloGene
  • Synonyms
    ORC6L
  • Links
    NCBI Gene ID: 23594
    neXtProt AC: NX_Q9Y5N6

  • Chr Location
    16q12; chr16:46689646-46698394 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8635
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ORC6
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human ORC6 associations

Human Disease Mouse Models
       Meier-Gorlin Syndrome 3; MGORS3   OMIM: 613803
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    33 phenotype references
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    15
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Orc6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031697 Ensembl Gene Model | MGI Sequence Detail 8647 C57BL/6J ±  kb
transcript ENSMUST00000034132 Ensembl | MGI Sequence Detail 1653 Not Applicable  
polypeptide ENSMUSP00000034132 Ensembl | MGI Sequence Detail 262 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    117 from dbSNP Build 137
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012035 origin recognition complex subunit 6
  • InterPro Domains
    IPR008721 Origin recognition complex, subunit 6
    IPR020529 Origin recognition complex, subunit 6, metazoa/plant
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 4
Other
Accession IDs
less
MGI:1924394
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 33
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory