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Cyb561d2 Gene Detail
Summary
  • Symbol
    Cyb561d2
  • Name
    cytochrome b-561 domain containing 2
  • Synonyms
    101F6 protein, Tsp10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929280
    NCBI Gene: 56368
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:107416210-107419392 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 58.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929280
 protein coding gene Chr9:107416206-107419392 (-)
129S1/SvImJ ENSMUSG00200039995
 protein coding gene Chr9:104611267-104614453 (-)
A/J ENSMUSG00195038671
 protein coding gene Chr9:103830038-103833224 (-)
AKR/J ENSMUSG00220023841
 protein coding gene Chr9:104219920-104223106 (-)
BALB/cJ ENSMUSG00180030750
 protein coding gene Chr9:104146493-104149679 (-)
C3H/HeJ ENSMUSG00175041178
 protein coding gene Chr9:104488810-104491996 (-)
C57BL/6NJ ENSMUSG00215033541
 protein coding gene Chr9:104466561-104469747 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032645
 protein coding gene Chr9:102864735-102867983 (-)
CAST/EiJ ENSTCUG00005025444
 protein coding gene Chr9:104239119-104242306 (-)
CBA/J ENSMUSG00210031724
 protein coding gene Chr9:104336701-104339887 (-)
DBA/2J ENSMUSG00185034063
 protein coding gene Chr9:104501544-104504730 (-)
FVB/NJ ENSMUSG00205049039
 protein coding gene Chr9:104499514-104502700 (-)
JF1/MsJ ENSUMUG00000054343
 protein coding gene Chr9:104325685-104328871 (-)
LP/J ENSMUSG00230049321
 protein coding gene Chr9:104640207-104643393 (-)
NOD/ShiLtJ ENSMUSG00190046016
 protein coding gene Chr9:104136703-104139889 (-)
NZO/HlLtJ ENSMUSG00225024388
 protein coding gene Chr9:104874323-104877509 (-)
PWK/PhJ ENSLUMG00010030304
 protein coding gene Chr9:104283981-104287168 (-)
SPRET/EiJ ENSMSPG00010038033
 protein coding gene Chr9:106114156-106117322 (-)
WSB/EiJ ENSIUOG00005040392
 protein coding gene Chr9:103583408-103586594 (-)



Homology
more
  • Human Ortholog
    CYB561D2, cytochrome b561 family member D2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYB561D2, cytochrome b561 family member D2
  • Synonyms
    101F6, TSCytb, TSP10, XXcos-LUCA11.4
  • Links
    NCBI Gene ID: 11068
    UniProt: O14569

  • Chr Location
    3p21.31; chr3:50350839-50358460 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    705
  • Tissues
    13
  • cDNA Data
    46
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56368 NCBI Gene Model | MGI Sequence Detail 3183 C57BL/6J ±  kb
    transcript NM_019720 RefSeq | MGI Sequence Detail 1788 C57BL/6  
    polypeptide Q9WUE3 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      cDNA 46

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143282
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 2
      Gene Ontology 11
      Phenotypes 7
    • Earliest
      J:66052 Lerman MI, et al., The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium [In Process Citation]. Cancer Res. 2000 Nov 1;60(21):6116-33
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory