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Ivd
Gene Detail
 Symbol
Name
ID
Ivd
isovaleryl coenzyme A dehydrogenase
MGI:1929242
Synonyms 1300016K07Rik, 6720455E18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
59.64 cM, cytoband E4-E5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:118861954-118882909 bp, + strand
From VEGA annotation of GRCm38

  20956 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1676  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ivd

Human
homologs
Human Homolog IVD, isovaleryl-CoA dehydrogenase
NCBI Gene ID 3712
neXtProt AC  NX_P26440
Human Synonyms  ACAD2
Human Chr (Location)  15q14-q15; chr15:40405485-40435947 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human IVD
Alleles
and
phenotypes
All alleles(4) : Targeted(3) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process leucine catabolic process, metabolic process, ...
Component mitochondrial matrix, mitochondrial membrane, ...
Function acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (10)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(9) Genomic(1) cDNA(8)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014828 (Evidence)
Ensembl Gene ModelENSMUSG00000027332 (Evidence)
Entrez Gene56357 (Evidence)
DFCITC1575886, TC1663299
DoTSDT.492898, DT.532181
NIA Mouse Gene IndexU002287
EC1.3.8.4
Consensus CDS ProjectCCDS16586.1
International Mouse Knockout Project StatusIvd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014828 VEGA Gene Model | MGI Sequence Detail 20956 C57BL/6J ±  kb
transcript OTTMUST00000035196 VEGA | MGI Sequence Detail 3665 Not Applicable 
polypeptide OTTMUSP00000015718 VEGA | MGI Sequence Detail 424 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(181 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006089 Acyl-CoA dehydrogenase, conserved site
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Protein Ontology PR:000009166 isovaleryl-CoA dehydrogenase, mitochondrial
References (Earliest) J:160670 Frerman FE, et al., Leucine catabolism during the differentiation of 3T3-L1 cells. Expression of a mitochondrial enzyme system. J Biol Chem. 1983 Jun 10;258(11):7087-93
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(35)
Other
accession IDs
MGI:1914156, MGI:1925136, MGI:2138971

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory