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Sap30 Gene Detail
Summary
  • Symbol
    Sap30
  • Name
    sin3 associated polypeptide
  • Synonyms
    30kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929129
    NCBI Gene: 60406
Location & Maps
more
  • Sequence Map
    Chr8:57482707-57487860 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5154 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SAP30, Sin3A associated protein 30kDa
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SAP30, Sin3A associated protein 30kDa
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 8819
    neXtProt AC: NX_O75446

  • Chr Location
    4q34.1; chr4:173370942-173377532 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Sap30
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029898 VEGA Gene Model | MGI Sequence Detail 5154 C57BL/6J ±  kb
transcript OTTMUST00000074177 VEGA | MGI Sequence Detail 1178 Not Applicable  
polypeptide OTTMUSP00000038507 VEGA | MGI Sequence Detail 220 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    5 from dbSNP Build 137
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000014448 histone deacetylase complex subunit SAP30
  • PDB
  • InterPro Domains
    IPR024145 Histone deacetylase complex subunit SAP30/SAP30-like
    IPR025718 Histone deacetylase complex subunit SAP30, Sin3 binding domain
    IPR025717 Histone deacetylase complex subunit SAP30 zinc-finger
Molecular
Reagents
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  • All nucleic 75
    Genomic 1
    cDNA 72
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:66985 Laherty CD, et al., SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell. 1998 Jul;2(1):33-42
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory