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Sap30 Gene Detail
Summary
  • Symbol
    Sap30
  • Name
    sin3 associated polypeptide
  • Synonyms
    30kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929129
    NCBI Gene: 60406
  • Gene Overview
    MyGene.info: SAP30
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:57482707-57487860 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 29.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929129
protein coding gene Chr8:57482702-57487860 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033623
protein coding gene Chr8:57211397-57216551 (-)
A/J MGP_AJ_G0033605
protein coding gene Chr8:54796641-54801795 (-)
AKR/J MGP_AKRJ_G0033530
protein coding gene Chr8:56426825-56431984 (-)
BALB/cJ MGP_BALBcJ_G0033602
protein coding gene Chr8:55119735-55124889 (-)
C3H/HeJ MGP_C3HHeJ_G0033311
protein coding gene Chr8:57081104-57086257 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034118
protein coding gene Chr8:59414979-59420132 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031066
protein coding gene Chr8:50348060-50353455 (-)
CAST/EiJ MGP_CASTEiJ_G0032637
protein coding gene Chr8:56471042-56476197 (-)
CBA/J MGP_CBAJ_G0033290
protein coding gene Chr8:61530684-61535994 (-)
DBA/2J MGP_DBA2J_G0033443
protein coding gene Chr8:54605276-54610427 (-)
FVB/NJ MGP_FVBNJ_G0033384
protein coding gene Chr8:53963463-53968614 (-)
LP/J MGP_LPJ_G0033531
protein coding gene Chr8:57219882-57225035 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033428
protein coding gene Chr8:63143207-63148661 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034136
protein coding gene Chr8:56660397-56665549 (-)
PWK/PhJ MGP_PWKPhJ_G0032345
protein coding gene Chr8:53917320-53922498 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032181
protein coding gene Chr8:55528199-55533387 (-)
WSB/EiJ MGP_WSBEiJ_G0032753
protein coding gene Chr8:56911118-56916283 (-)



Homology
more
  • Human Ortholog
    SAP30, Sin3A associated protein 30
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SAP30, Sin3A associated protein 30
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8819
    neXtProt AC: NX_O75446
    UniProt: O75446

  • Chr Location
    4q34.1; chr4:173370942-173377532 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031609 Ensembl Gene Model | MGI Sequence Detail 5154 C57BL/6J ±  kb
transcript ENSMUST00000034022 Ensembl | MGI Sequence Detail 1178 Not Applicable  
polypeptide ENSMUSP00000034022 Ensembl | MGI Sequence Detail 220 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000014448 histone deacetylase complex subunit SAP30
  • PDB
  • InterPro Domains
    IPR024145 Histone deacetylase complex subunit SAP30/SAP30-like
    IPR025718 Histone deacetylase complex subunit SAP30, Sin3 binding domain
    IPR025717 Histone deacetylase complex subunit SAP30 zinc-finger
    IPR038291 SAP30, C-terminal domain superfamily
Molecular
Reagents
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  • All nucleic 76
    Genomic 1
    cDNA 73
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:66985 Laherty CD, et al., SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell. 1998 Jul;2(1):33-42
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory