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Sap30
Gene Detail
Symbol

Name
ID
Sap30
sin3 associated polypeptide
MGI:1929129
Synonyms
30kDa
Feature Type
protein coding gene
Genetic Map
Chromosome 8
29.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:57482707-57487860 bp, - strand
From VEGA annotation of GRCm38

  5154 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2869  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Protein SuperFamily: histone deacetylase complex, SAP30/SAP30L subunits
Gene Tree: Sap30

Human
homologs
Human Homolog SAP30, Sin3A-associated protein, 30kDa
NCBI Gene ID 8819
neXtProt AC  NX_O75446
Human Chr (Location)  4q34.1; chr4:173370942-173377532 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sap30 interacts with 57 markers (Mir7-2, Mir7b, Mir30a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (52)    Tissues (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 16
RT-PCR 36
cDNA source data(72)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(75) Genomic(1) cDNA(72) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000029898 (Evidence)
Ensembl Gene ModelENSMUSG00000031609 (Evidence)
Entrez Gene60406 (Evidence)
UniGene118
DFCITC1578944
DoTSDT.535291
NIA Mouse Gene IndexU029840
PDB2LD7
Consensus CDS ProjectCCDS22316.1
International Mouse Knockout Project StatusSap30
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029898 VEGA Gene Model | MGI Sequence Detail 5154 C57BL/6J ±  kb
transcript OTTMUST00000074177 VEGA | MGI Sequence Detail 1178 Not Applicable 
polypeptide OTTMUSP00000038507 VEGA | MGI Sequence Detail 220 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(5 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024145 Histone deacetylase complex subunit SAP30/SAP30-like
InterPro IPR025718 Histone deacetylase complex subunit SAP30, Sin3 binding domain
InterPro IPR025717 Histone deacetylase complex subunit SAP30 zinc-finger
Protein Ontology PR:000014448 histone deacetylase complex subunit SAP30
References
(Earliest) J:66985 Laherty CD, et al., SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell. 1998 Jul;2(1):33-42
(Latest) J:178918 Rajan S, et al., Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Physiol Genomics. 2011 Dec 6;
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory