About   Help   FAQ
Stam2 Gene Detail
Summary
  • Symbol
    Stam2
  • Name
    signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
  • Synonyms
    1200004O12Rik, 5730456G07Rik, Hbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929100
    NCBI Gene: 56324
  • Gene Overview
    MyGene.info: STAM2
Location & Maps
more
  • Sequence Map
    Chr2:52691664-52742281 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      50618 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 30.41 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    STAM2, signal transducing adaptor molecule 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STAM2, signal transducing adaptor molecule 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Hbp, STAM2A, STAM2B
  • Links
    NCBI Gene ID: 10254
    neXtProt AC: NX_O75886

  • Chr Location
    2q23.3; chr2:152116801-152175992 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 68490
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 frog, western clawed
  • HCOP
    human homology predictions: STAM2
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    12 phenotype references
  • All Mutations and Alleles
    35
  • Chemically induced (other)
    1
  • Gene trapped
    31
  • Targeted
    3
  • Genomic Mutations
    1 involving Stam2
  • Incidental Mutations
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal lymphocyte responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012637 VEGA Gene Model | MGI Sequence Detail 50618 C57BL/6J ±  kb
transcript OTTMUST00000030072 VEGA | MGI Sequence Detail 4717 Not Applicable  
polypeptide OTTMUSP00000013521 VEGA | MGI Sequence Detail 523 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    131 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 80
    cDNA 79
    Other 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:1917833, MGI:1918967, MGI:2139437
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:180803 Gajovic S, et al., Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development. Exp Cell Res. 1998 Jul 10;242(1):138-43
  • Latest
    J:226940 Kapuralin K, et al., STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons. Mol Cell Neurosci. 2015 Jul;67:104-15

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/23/2016
MGI 6.05
The Jackson Laboratory