Stam2
Gene Detail

Symbol Name ID

Stam2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 MGI:1929100

Synonyms

1200004O12Rik, 5730456G07Rik, Hbp

Feature Type

protein coding gene

Genetic Map

Chromosome 2

30.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:52691664-52742281 bp, - strand From VEGA annotation of GRCm38   50618 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68490  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: STAM
Gene Tree: Stam2

Human homologs

Human Homolog		STAM2, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
NCBI Gene ID		10254
neXtProt AC		NX_O75886
Human Synonyms		Hbp, STAM2A, STAM2B
Human Chr (Location)		2q23.3; chr2:152973315-153032506 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(34) : Targeted(3) Gene trapped(31)
 

Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal lymphocyte responses.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	intracellular protein transport, protein transport, ...
Component	cytoplasm, endosome, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (420)    Tissues (227)    Images (35)
Theiler Stages: 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26

Assay Type	Results
Immunohistochemistry	39
RNA in situ	52
In situ reporter (knock in)	329

cDNA source data(77)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(80) cDNA(79) Other(1)
Microarray probesets(12)

Other database links

VEGA Gene Model	OTTMUSG00000012637 (Evidence)
Ensembl Gene Model	ENSMUSG00000055371 (Evidence)
Entrez Gene	56324 (Evidence)
UniGene	263639
DFCI	TC1572704, TC1591285, TC1659853, TC1717745
DoTS	DT.103572508, DT.110706251, DT.531168, DT.55136389, DT.91386437, DT.94193251
NIA Mouse Gene Index	U022631
PDB	1UJ0
Consensus CDS Project	CCDS16037.1
International Mouse Knockout Project Status	Stam2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000012637	VEGA Gene Model | MGI Sequence Detail	50618	C57BL/6J
transcript	OTTMUST00000030072	VEGA | MGI Sequence Detail	4717	Not Applicable
polypeptide	OTTMUSP00000013521	VEGA | MGI Sequence Detail	523	Not Applicable

All sequences(59) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(123 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008942	ENTH/VHS
InterPro	IPR000108	Neutrophil cytosol factor 2 p67phox
InterPro	IPR001452	Src homology-3 domain
InterPro	IPR003903	Ubiquitin interacting motif
InterPro	IPR002014	VHS
InterPro	IPR018205	VHS subgroup
Protein Ontology	PR:000015710	signal transducing adapter molecule 2

References

(Earliest) J:180803 Gajovic S, et al., Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development. Exp Cell Res. 1998 Jul 10;242(1):138-43
(Latest) J:185949 Licatalosi DD, et al., Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes Dev. 2012 Jul 15;26(14):1626-42
All references(39)

Other accession IDs

MGI:1917833, MGI:1918967, MGI:2139437