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Sinhcaf Gene Detail
Summary
  • Symbol
    Sinhcaf
  • Name
    SIN3-HDAC complex associated factor
  • Synonyms
    Fam60a, Pptcs1, Tera
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929091
    NCBI Gene: 56306
  • Gene Overview
    MyGene.info: SINHCAF
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:148921057-148946432 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 78.67 cM, cytoband G3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929091
protein coding gene Chr6:148921035-148946467 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031506
protein coding gene Chr6:154031474-154062368 (-)
A/J MGP_AJ_G0031481
protein coding gene Chr6:147915054-147942356 (-)
AKR/J MGP_AKRJ_G0031409
protein coding gene Chr6:152334811-152362872 (-)
BALB/cJ MGP_BALBcJ_G0031489
protein coding gene Chr6:147678361-147704023 (-)
C3H/HeJ MGP_C3HHeJ_G0031210
protein coding gene Chr6:152389283-152418453 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031950
protein coding gene Chr6:158118845-158133067 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029074
protein coding gene Chr6:146640516-146663712 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031170
protein coding gene Chr6:164199424-164225070 (-)
DBA/2J MGP_DBA2J_G0031326
protein coding gene Chr6:146714699-146735188 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0031412
protein coding gene Chr6:154168271-154195277 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031318
protein coding gene Chr6:167832946-167868623 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031983
protein coding gene Chr6:152178123-152203709 (-)
PWK/PhJ MGP_PWKPhJ_G0030305
protein coding gene Chr6:145226426-145252538 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030129
protein coding gene Chr6:150290629-150309188 (-)
WSB/EiJ MGP_WSBEiJ_G0030672
protein coding gene Chr6:152795238-152821199 (-)



Homology
more
  • Human Ortholog
    SINHCAF, SIN3-HDAC complex associated factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SINHCAF, SIN3-HDAC complex associated factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf14, FAM60A, L4, TERA
  • Links
    NCBI Gene ID: 58516
    neXtProt AC: NX_Q9NP50
    UniProt: Q9NP50

  • Chr Location
    12p11.21; chr12:31280584-31326225 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56306 NCBI Gene Model | MGI Sequence Detail 25376 C57BL/6J ±  kb
transcript NM_001355645 RefSeq | MGI Sequence Detail 2737 C57BL/6  
polypeptide Q8C8M1 UniProt | EBI | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 125
    cDNA 121
    Primer pair 3
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1097676
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:42329 Saijoh Y, et al., Identification of putative downstream genes of Oct-3, a pluripotent cell-specific transcription factor. Genes Cells. 1996 Feb;1(2):239-52
  • Latest
    J:243422 Streubel G, et al., Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal. EMBO J. 2017 Aug 01;36(15):2216-2232

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory